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. Author manuscript; available in PMC: 2021 Dec 1.
Published in final edited form as: Clin Chest Med. 2020 Dec;41(4):825–843. doi: 10.1016/j.ccm.2020.08.014

Table 1.

Mechanism by Which Household Pollution Can Impact Respiratory Health

• Neutrophilic Inflammation
• Reduced Bacterial Clearance and Alterations in Microbiome
• Increased Matrix Metalloproteinase Activity and Gene Expression
• Greater Oxidative Stress
• Increased Apoptosis
• Pulmonary Surfactant Deactivation
• Reduced Mucociliary Clearance
• Epigenetic Changes - DNA Damage and Methylation
• Disruption of Lung Endothelial Cell Barrier