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. 2020 Nov 12;10:399. doi: 10.1038/s41398-020-01084-x

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Normalized mRNA expression of angiotensinogen (Agt), apolipoprotein C2 (Apoc2), and complement 4b (C4b) in SZ vs. control dlPFC gray matter. These mRNAs are components of the canonical pathway “LXR/RXR activation” in the Ingenuity pathway analysis. b Normalized mRNA expression of the LXR/RXR signaling cascade components Liver X receptor β (Lxrβ), retinoid X receptor β (Rxrβ), ATP-binding cassette transporter A1 (Abca1), peripheral myelin protein 22 (Pmp22), apolipoprotein E (ApoE), and sterol regulatory element-binding protein 1 (SREBP1) in SZ vs. control dlPFC gray matter. c, d Normalized mRNA expression of the same genes as in a and b in the white matter of dlPFC. n = 4 samples per group, #p < 0.1, *p < 0.05 in independent samples T-test.