Table 2.
Metabolites that share significant genetic etiology with SZ.
| Metabolite | Lowest significant p-value treshold | Bonferroni- corrected p-value | Lowest significant p-value treshold | Bonferroni- corrected p-value |
|---|---|---|---|---|
| SZ GWAS 201840 | SZ GWAS 201448 | |||
| C5.1.DC1 | 0.1 | 0.000246 | 0.05 | 0.015176 |
| IP105 | 0.3 | 0.000997 | 0.05 | 0.048767 |
| CH2.DB.ratio2 | 0.1 | 0.00153 | 0.1 | 0.014121 |
| LPE16_0_LIPID4 | 0.001 | 0.001988 | 0.001 | 0.000768 |
| XS.VLDL.TG3 | 0.2 | 0.002406 | 0.3 | 0.039835 |
| C14.1.OH1 | 0.05 | 0.002534 | 0.05 | 0.008502 |
| DB.in.FA2 | 0.1 | 0.003962 | 0.1 | 0.010729 |
| XS.VLDL.P3 | 0.3 | 0.004685 | 0.2 | 0.008044 |
| IDL.C3 | 0.05 | 0.006454 | NA | NA |
| PC38_2_LIPID4 | 0.3 | 0.007062 | 0.2 | 0.000573 |
| CH2.in.FA2 | 0.2 | 0.008944 | 0.1 | 0.006678 |
| Bis.DB.ratio2 | 0.2 | 0.009453 | 0.05 | 0.018628 |
| DHA2 | 0.4 | 0.010114 | 0.05 | 0.00935 |
| SM.C26.04 | 0.1 | 0.010245 | 0.05 | 0.002634 |
| XS.VLDL.L3 | 0.05 | 0.010881 | 0.2 | 7.49E-05 |
| TAG54_6_LIPID4 | 0.001 | 0.016009 | 0.001 | 0.009793 |
| SM.OH.C24.14 | 0.1 | 0.017865 | 0.05 | 0.006078 |
| FAw34 | 0.05 | 0.01807 | 0.05 | 0.002175 |
| fumarate_maleate_valerat_CMH | 0.05 | 0.019523 | 0.05 | 0.001032 |
| Ratio_PC3806_LPC2206_LIPID4 | 0.05 | 0.023256 | NA | NA |
| IDL.FC3 | 0.4 | 0.024663 | NA | NA |
| LPC20_3_LIPID4 | 0.3 | 0.026304 | NA | NA |
| XS.VLDL.PL3 | 0.05 | 0.027834 | 0.2 | 0.00178 |
| XL.VLDL.TG3 | 0.3 | 0.032077 | 0.3 | 0.001178 |
| PC32_0_LIPID4 | 0.1 | 0.032928 | 0.1 | 0.000627 |
| PC.ae.C44.34 | 0.1 | 0.034516 | NA | NA |
| IDL.L3 | 0.1 | 0.034726 | NA | NA |
| S.VLDL.C3 | 0.4 | 0.035649 | 0.4 | 0.047852 |
| IDL.P3 | 0.1 | 0.036891 | NA | NA |
| lysoPC.a.C20.44 | 0.3 | 0.039526 | 0.2 | 0.019734 |
| Bis.FA.ratio2 | 0.1 | 0.040777 | 0.05 | 0.005426 |
| S.VLDL.L3 | 0.5 | 0.0408 | NA | NA |
| GROa | 0.001 | 0.042828 | NA | NA |
| MCP1 | 0.001 | 0.045366 | 0.001 | 0.001432 |
| LPC22_6_LIPID4 | 0.1 | 0.048797 | NA | NA |
| Cit | NA | NA | 0.05 | 0.00031 |
| PCB36_4_LIPID4 | NA | NA | 0.05 | 0.000894 |
| PC38_6_LIPID4 | NA | NA | 0.1 | 0.002651 |
| CE20_5_LIPID3 | NA | NA | 0.2 | 0.002948 |
| TAG56_6_LIPID4 | NA | NA | 0.2 | 0.005974 |
| PC40_6_LIPID4 | NA | NA | 0.3 | 0.008719 |
| PC.aa.C24.04 | NA | NA | 0.1 | 0.010428 |
| TAG56_8_LIPID4 | NA | NA | 0.2 | 0.012203 |
| IL165 | NA | NA | 0.05 | 0.01252 |
| TAG58_10_LIPID4 | NA | NA | 0.3 | 0.014247 |
| TAG56_6_LIPID4 | NA | NA | 0.3 | 0.020381 |
| XXL.VLDL.PL3 | NA | NA | 0.3 | 0.027232 |
| L.VLDL.P3 | NA | NA | 0.05 | 0.030895 |
| XL.HDL.L3 | NA | NA | 0.5 | 0.032042 |
| aconitate_CMH | NA | NA | 0.1 | 0.032102 |
| XL.VLDL.L3 | NA | NA | 0.4 | 0.03703 |
| TAG58_11_LIPID4 | NA | NA | 0.3 | 0.037887 |
| PC38_4_LIPID4 | NA | NA | 0.4 | 0.038142 |
| LDL.D3 | NA | NA | 0.001 | 0.042824 |
| FAw64 | NA | NA | 0.05 | 0.044601 |
| ADP_CMH | NA | NA | 0.4 | 0.049512 |
1Acylcarnitines.
2Fatty acids.
3Cholesterols.
4Other lipids.
5Immune-related cytokines.