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. 2020 Nov 12;10:19686. doi: 10.1038/s41598-020-76698-8

Figure 4.

Figure 4

EMPA treatment affects cardiac tissue cytokine expression (a) mRNA expression of EGF-like module-containing mucin-like hormone receptor-like 1 (F 4/80), Interleukin-6 (Il-6), Chemokine ligand 2 (Ccl2), chemokine receptor type 2 (Ccr2), Interleukin-10 (Il-10), macrophage galactose-type lectin-1 (Mgl1) and C-type mannose receptor 2 (Mrc2). (b) Representative western blot of phospho-NF-κB Ser536 and total NF-κB with respective ratio (c) of phospho-NF-κB Ser 536 over total NF-κB. Data are expressed as means ± SEM, n = 8–10, *p < 0.05, **p < 0.01, n.s. = not significant. Full-length images of cropped gels/blots are available in Supplementary Fig. 4. WD, Western type diet only; EMPA, Western type diet enriched with empagliflozin.