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. 2020 Nov 12;3:666. doi: 10.1038/s42003-020-01386-2

Fig. 2. WNK regulates the protein level of β-Catenin through the GID complex.

Fig. 2

a Western blot analysis of β-Catenin following the knockdown of both WNK1 and WNK4 in HEK293T cells. GFP is co-transfected for checking the transfection efficiency. b Western blot analysis of endogenous β-Catenin following the knockdown of WNK1 and/or WNK4 in SW480 cells. c–f Western blot analysis of endogenous β-Catenin following the knockdown of both WNK1 and WNK4, or the knockdown of βTrCP and/or βTrCP2 (c), SIAH1 (d), SHPRH (e), or RMND5A, and/or MAEA (f) in SW480 cells.