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. 2020 Nov 12;3:663. doi: 10.1038/s42003-020-01375-5

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a and b. Confocal fluorescence sections of hb_ant and Kr_CD2 embryos just before gastrulation. c and d. total mRNA levels along the AP axis over time. Averages from three replicates of each enhancer. The inset in (d) zooms in on the evolution of the central stripe of the Kr_CD2 enhancer. The red line highlights the dynamic shift of the position of the expression peak. e and f. Total mRNA levels as a function of time, with AP position color-coded as indicated. Averages from three replicates of each enhancer. g Temporal dynamics for the anterior domain (dots) and the posterior/central stripe (crosses) of the two enhancers.