Table 1. Univariate and multivariate analyses of clinicopathological factors affecting OS after laparoscopic gastrectomy for gastric cancer.
Variables | Univariate analysis | Multivariate analysis with GPS | Multivariate analysis with mGPS | Multivariate analysis with HS-mGPS | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | ||
Age | < 70 | 1.000 | |||||||||||
≥ 70 | 1.617 | 1.044–2.505 | 0.032 | 1.175 | 0.730–1.892 | 0.506 | 1.202 | 0.747–1.934 | 0.448 | 1.236 | 0.771–1.982 | 0.378 | |
Gender | female | 1.000 | |||||||||||
Male | 1.604 | 0.974–2.642 | 0.063 | ||||||||||
BMI | ≥ 18.5 | 1.000 | |||||||||||
< 18.5 | 1.905 | 1.075–3.375 | 0.027 | 1.723 | 0.950–3.126 | 0.073 | 1.942 | 1.077–3.504 | 0.027 | 1.923 | 1.070–3.459 | 0.029 | |
Tumor size | < 5 | 1.000 | |||||||||||
≥ 5 | 2.334 | 1.525–3.573 | < 0.001 | 1.108 | 0.636–1.930 | 0.716 | 1.238 | 0.709–2.162 | 0.453 | 1.135 | 0.645–1.996 | 0.661 | |
Diff. | well & mod | 1.000 | |||||||||||
Poor | 1.656 | 1.087–2.522 | 0.019 | 1.459 | 0.922–2.308 | 0.107 | 1.427 | 0.901–2.261 | 0.130 | 1.426 | 0.904–2.251 | 0.127 | |
pSstage | 1 & 2 | 1.000 | |||||||||||
3 | 4.000 | 2.612–6.125 | < 0.001 | 2.817 | 1.638–4.844 | <0.001 | 2.747 | 1.583–4.766 | < 0.001 | 2.890 | 1.680–4.971 | < 0.001 | |
CEA | < 5.0 | 1.000 | |||||||||||
≥ 5.0 | 2.350 | 1.528–3.612 | < 0.001 | 1.942 | 1.239–3.044 | 0.004 | 1.958 | 1.248–3.070 | < 0.001 | 1.963 | 1.253–3.076 | 0.003 | |
GPS | 0 | 1.000 | |||||||||||
1 | 2.602 | 1.594–4.245 | < 0.001 | 1.929 | 1.152–3.228 | 0.013 | |||||||
2 | 5.240 | 2.722–10.089 | < 0.001 | 1.887 | 0.837–4.254 | 0.126 | |||||||
mGPS | 0 | 1.000 | 1.000 | ||||||||||
1 | 2.681 | 1.163–6.183 | 0.021 | 2.299 | 0.960–5.505 | 0.062 | |||||||
2 | 4.041 | 2.133–7.657 | < 0.001 | 1.631 | 0.736–3.613 | 0.228 | |||||||
HS-mGPS | 0 | 1.000 | 1.000 | ||||||||||
1 | 1.568 | 0.860–2.861 | 0.142 | ||||||||||
2 | 3.660 | 2.103–6.370 | < 0.001 | 1.610 | 0.835–3.104 | 0.155 | |||||||
Complications | Absent | 1.000 | |||||||||||
Present | 1.876 | 1.220–2.884 | 0.004 | 1.445 | 0.890–2.346 | 0.136 | 1.428 | 0.874–2.331 | 0.155 | 1.473 | 0.912–2.380 | 0.113 |