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. 2020 Nov 10;11(45):4169–4177. doi: 10.18632/oncotarget.27796

Table 1. Univariate and multivariate analyses of clinicopathological factors affecting OS after laparoscopic gastrectomy for gastric cancer.

Variables Univariate analysis Multivariate analysis with GPS Multivariate analysis with mGPS Multivariate analysis with HS-mGPS
HR 95% CI p value HR 95% CI p value HR 95% CI p value HR 95% CI p value
Age < 70 1.000
≥ 70 1.617 1.044–2.505 0.032 1.175 0.730–1.892 0.506 1.202 0.747–1.934 0.448 1.236 0.771–1.982 0.378
Gender female 1.000
Male 1.604 0.974–2.642 0.063
BMI ≥ 18.5 1.000
< 18.5 1.905 1.075–3.375 0.027 1.723 0.950–3.126 0.073 1.942 1.077–3.504 0.027 1.923 1.070–3.459 0.029
Tumor size < 5 1.000
≥ 5 2.334 1.525–3.573 < 0.001 1.108 0.636–1.930 0.716 1.238 0.709–2.162 0.453 1.135 0.645–1.996 0.661
Diff. well & mod 1.000
Poor 1.656 1.087–2.522 0.019 1.459 0.922–2.308 0.107 1.427 0.901–2.261 0.130 1.426 0.904–2.251 0.127
pSstage 1 & 2 1.000
3 4.000 2.612–6.125 < 0.001 2.817 1.638–4.844 <0.001 2.747 1.583–4.766 < 0.001 2.890 1.680–4.971 < 0.001
CEA < 5.0 1.000
≥ 5.0 2.350 1.528–3.612 < 0.001 1.942 1.239–3.044 0.004 1.958 1.248–3.070 < 0.001 1.963 1.253–3.076 0.003
GPS 0 1.000
1 2.602 1.594–4.245 < 0.001 1.929 1.152–3.228 0.013
2 5.240 2.722–10.089 < 0.001 1.887 0.837–4.254 0.126
mGPS 0 1.000 1.000
1 2.681 1.163–6.183 0.021 2.299 0.960–5.505 0.062
2 4.041 2.133–7.657 < 0.001 1.631 0.736–3.613 0.228
HS-mGPS 0 1.000 1.000
1 1.568 0.860–2.861 0.142
2 3.660 2.103–6.370 < 0.001 1.610 0.835–3.104 0.155
Complications Absent 1.000
Present 1.876 1.220–2.884 0.004 1.445 0.890–2.346 0.136 1.428 0.874–2.331 0.155 1.473 0.912–2.380 0.113