Table 2. Univariate and multivariate analyses of clinicopathological factors affecting CSS after laparoscopic gastrectomy for gastric cancer.
Variables | Univariate analysis | Multivariate analysis with GPS | Multivariate analysis with mGPS | Multivariate analysis with HS-mGPS | |||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | HR | 95% CI | p value | ||
Age | < 70 | 1.000 | |||||||||||
≥ 70 | 1.072 | 0.592–1.940 | 0.820 | ||||||||||
Gender | female | 1.000 | |||||||||||
Male | 1.573 | 0.777–3.185 | 0.208 | ||||||||||
BMI | ≥ 18.5 | 1.000 | |||||||||||
< 18.5 | 1.636 | 0.691–3.871 | 0.263 | ||||||||||
Tumor size | < 5 | 1.000 | |||||||||||
≥ 5 | 3.848 | 2.013–7.356 | < 0.001 | 1.074 | 0.484–2.385 | 0.860 | 1.142 | 0.511–2.553 | 0.746 | 1.105 | 0.491–2.485 | 0.809 | |
Diff. | well & mod | 1.000 | |||||||||||
Poor | 1.899 | 1.041–3.465 | 0.037 | 1.519 | 0.783–2.948 | 0.216 | 1.565 | 0.809–3.027 | 0.184 | 1.521 | 1.521–2.923 | 0.209 | |
pSstage | 1 & 2 | 1.000 | |||||||||||
3 | 9.778 | 5.002–19.113 | < 0.001 | 6.624 | 2.973–14.757 | <0.001 | 6.941 | 3.098–15.549 | < 0.001 | 7.063 | 3.182–15.678 | < 0.001 | |
CEA | < 5.0 | 1.000 | |||||||||||
≥ 5.0 | 2.745 | 1.511–4.987 | < 0.001 | 2.162 | 1.165–4.014 | 0.015 | 2.207 | 1.186–4.107 | 0.013 | 2.300 | 1.236–4.279 | 0.009 | |
GPS | 0 | 1.000 | |||||||||||
1 | 2.308 | 1.188–4.485 | 0.014 | 2.095 | 1.025–4.283 | 0.043 | |||||||
2 | 6.442 | 3.087–13.441 | < 0.001 | 2.812 | 1.111–7.116 | 0.029 | |||||||
mGPS | 0 | 1.000 | 1.000 | ||||||||||
1 | 2.258 | 0.698–7.302 | 0.174 | ||||||||||
2 | 6.442 | 3.087–13.441 | < 0.001 | 2.241 | 0.926–5.426 | 0.074 | |||||||
HS-mGPS | 0 | 1.000 | 1.000 | ||||||||||
1 | 1.253 | 0.530–2.965 | 0.607 | ||||||||||
2 | 5.120 | 2.585–10.142 | < 0.001 | 2.040 | 0.917–4.535 | 0.080 | |||||||
Complication | Absent | 1.000 | |||||||||||
Present | 1.802 | 0.981–3.310 | 0.058 |