Table 1. Encyclopedic tumor analysis (ETA) findings.

Sample Type Received	Gene Name	Molecular alteration
(left supraclavicular node biopsy)	TP53 p. C141R	SNV (32% MAF)
	TP53 p. R158C	SNV (2.2% MAF)
	CDKN2A p. G122D	SNV (2.9% MAF)
	ABL1 p. T315I	SNV (2.1% MAF)
	SYNE1 p. K7182fs*17	SNV (4.6% MAF)
	CDK12, PGAP3, ERBB2 (17q12 - 17q12)	CNV (18 gain)
	CCNE1 (19q12 - 19q12)	CNV (14 gain)
	AR (IHC)	Negative
Blood	Chemo-sensitivity on C-TACs	Cyclophosphamide 38% and Methotrexate 44% CD

MAF – Mutant allele frequency; SNV – Single nucleotide variation; CNV – copy number variation; DGE – Differential gene expression; C-TACs – Circulating Tumor Associated cells; CD – Cell death.