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. 2020 Nov 2:aqaa221. doi: 10.1093/ajcp/aqaa221

Table 4.

Effect of Prevalence on Positive Predictive Value (PPV), Negative Predictive Value (NPV), and Overall Accuracy

Prevalence (%) PPV (%) NPV (%) Accuracy (%)
5 74.01a 99.82 98.13
10 85.74 99.62 98.05
20 93.12 99.14 97.89

aAt 5% prevalence, if the sensitivity is 100%, the PPV increases to only 75%.

Calculations assume a sensitivity of 96.61% and a specificity of 98.21%.