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. 2020 Nov 5:agaa096. doi: 10.1093/alcalc/agaa096

Table 1.

Case by case description of reaction with disulfiram

Serial number Age (years) Medical comorbidity Disulfiram ethanol reaction Isopropanol toxicity Need for medical attention Sanitizer particulars Behaviour change Possible hypothesis
Description Frequency Description Frequency Nature Daily use (ml) Change in medication adherence Change in handwashing practice
1 51 No Heat and redness over face and neck, Heat and sweating all over body Rare NIL NA No Ethanol 6 No Hand wash with soap-water Possible inhalation
2 35 No More than usual amount heat and redness over hands, heat and sweating over the body Rare NIL NA No Isopropanol 25 No None Higher amount, inhalational
3 29 No Heat and sweating over hands and all over body if more amount is used, Nausea and vomiting, vertigo Frequent NIL NA No Both 6 No Hand wash with soap-water Higher amount, inhalational
4 37 No Heat and redness over hands, Occasional difficulty in breathing, Palpitations and chest discomfort, anxiety, restlessness Frequent NIL NA No Isopropanol 5 Yes Hand wash with soap-water Usual amount—local reaction. Generalised reaction—Higher amount, inhalational
5 41 HTN Difficulty in breathing, weakness, fatigue, giddiness, confusion after being sprayed with more than usual amount of sanitizer Frequent Dizziness, Ataxia Rare Yes Isopropanol 4 No Hand wash with soap-water Higher amount and spraying inhalational
6 42 No Heat and redness over face and neck, Nausea and vomiting, Difficulty in breathing, Anxiety, restlessness, Weakness, fatigue, Giddiness Frequent Dizziness, Palpitations Frequent No Both 15 Yes Hand wash with soap-water Absorption from Moist hand
7 40 No Heat and redness over hands. Self-limiting Frequent Dizziness, Palpitations Frequent No Both 6 No Non-alcoholic hand rub Local reaction after exposure
8 34 CAD Heat and redness over face and neck (no local reaction) Once Dizziness, palpitation, Ataxia Once Yes Both 10 Yes None Systemic reaction after exposure