Table 1.
GO terms, GO pathways and their corresponding P-values and genes for common differentially expressed genes
| Category | GO ID | GO pathways | P-values | Genes |
|---|---|---|---|---|
| GO biological process | GO:0070486 | Leukocyte aggregation | 0.000005766 | S100A9, S100A8 |
| GO:0050832 | Defense response to fungus | 8.380e-8 | S100A12, S100A9, S100A8 | |
| GO:0030593 | Neutrophil chemotaxis | 1.430e-8 | SAA1, S100A12, S100A9, S100A8 | |
| GO:0071621 | Granulocyte chemotaxis | 1.792e-8 | SAA1, S100A12, S100A9, S100A8 | |
| GO:1990266 | Neutrophil migration | 2.069e-8 | SAA1, S100A12, S100A9, S100A8 | |
| GO:1900122 | Positive regulation of receptor binding | 0.003296 | MMP9 | |
| GO:0002693 | Positive regulation of cellular extravasation | 0.003296 | ICAM1 | |
| GO:0032364 | Oxygen homeostasis | 0.003296 | SOD2 | |
| GO:0003085 | Negative regulation of systemic arterial blood pressure | 0.003296 | SOD2 | |
| GO:0051549 | Positive regulation of keratinocyte migration | 0.003296 | MMP9 | |
| GO Molecular Function | GO:0050786 | RAGE receptor binding | 1.038e-8 | S100A12, S100A9, S100A8 |
| GO:0035325 | Toll-like receptor binding | 0.000009879 | S100A9, S100A8 | |
| GO:0046914 | Transition metal ion binding | 0.000001290 | S100A12, SOD2, MMP9, S100A9, S100A8 | |
| GO:0008270 | Zinc ion binding | 0.00001547 | S100A12, MMP9, S100A9, S100A8 | |
| GO:0004866 | Endopeptidase inhibitor activity | 0.001625 | SERPINA3, PI3 | |
| GO:0030145 | Manganese ion binding | 0.01909 | SOD2 | |
| GO:0030414 | Peptidase inhibitor activity | 0.01963 | PI3 | |
| GO:0061135 | Endopeptidase regulator activity | 0.01963 | PI3 | |
| GO:0005507 | Copper ion binding | 0.02233 | S100A12 | |
| GO:0046872 | Metal ion binding | 0.00006865 | S100A12, SOD2, S100A9, S100A8 | |
| GO Cellular Component | GO:0060205 | Cytoplasmic vesicle lumen | 4.624e-9 | SERPINA3, SAA1, S100A12, S100A9, S100A8 |
| GO:0071682 | Endocytic vesicle lumen | 0.009858 | SAA1 | |
| GO:0034774 | Secretory granule lumen | 0.00001872 | SERPINA3, S100A12, S100A9, S100A8 | |
| GO:0005881 | Cytoplasmic microtubule | 0.02071 | SAA1 | |
| GO:1904724 | Tertiary granule lumen | 0.02984 | MMP9 | |
| GO:0031093 | Platelet alpha granule lumen | 0.03625 | SERPINA3 | |
| GO:0045111 | Intermediate filament cytoskeleton | 0.03837 | S100A8 | |
| GO:0005856 | Cytoskeleton | 0.002467 | S100A12, S100A9, S100A8 | |
| GO:0031091 | Platelet alpha granule | 0.04841 | SERPINA3 | |
| GO:0035578 | Azurophil granule lumen | 0.04841 | SERPINA3 |