Table 1.

Risk Factors for Development of Fournier Gangrene

Demographic	Male sex Advanced age (>50 years) Spinal cord injury26 Obesity (BMI >30 kg/m2) Malnourishment Recent trauma or surgery Structural or functional anatomic defects Urethral stricture27 Inguinal hernia28 Rectal fistula Perianal abscess29 Lower extremity paralysis25 Neurogenic bladder26
Vascular Disease	Peripheral vascular disease Hypertension
Immunocompromised State	Diabetes mellitus HIV/AIDS Chronic/high-dose steroid use Cytotoxic drugs including chemotherapy Lymphoproliferative diseases Leukemia30 Systemic lupus erythematosus Inflammatory bowel disease31 Rectal/colon malignancy
Drug Use	Alcohol use Tobacco use Stimulant use Injection drug use SGLT2 inhibitor use20
Chronic Organ Dysfunction	Chronic kidney disease Hepatic insufficiency Heart failure
Iatrogenic/Procedural	Urologic Urinary catheterization or instrumentation Prostatic biopsy Vasectomy Urethral stricture manipulation
	Gastrointestinal Pancreatic stent dislocation Inguinal hernia repair32 Rectal biopsy
	Gynecologic Episiotomy wound/repair Hysterectomy24

Note: Data from these studies.^{9,15,20,22–25}