Table 5.

Table of codons for residues at 24 RBD binding sites in SARS-CoV-2 and corresponding residues in 12 CoV strains

Pos	SARS- CoV-2	Bat-CoV- RaTG13	Pangolin- CoV-17	Pangolin- CoV-19	Bat-SL-CoV- ZXC21	Bat-SL- CoV-ZC45	SARS-CoV	Civet- SARS-CoV	Rs4231	WIV16	Rs4874	WIV1	HKU3
1249	AAG	AAG	GTT	AGA	GTT	GTC	GTT	GTT	GTT	GTT	GTT	GTT	GTT
1315	AAC	AAG	GTT	AAC	GCA	GCC	AGG	AGG	AAT	AGG	AGG	AGG	GCT
1333	GTT	GAG	ACT	GTT	AAA	AAA	TCA	TCA	ACT	CAA	CAA	CAA	AAA
1336	GGT	GGC	GGT	GGT	–	–	ACT	ACT	TCC	ACT	ACT	ACT	–
1345	TAT	TTT	TAT	TAT	–	–	TAT	TAT	TAT	TAT	TAT	TAT	–
1357	TAT	TAC	TAT	TAT	TAT	TAC	TAT	TAT	TAT	TAT	TAT	TAT	TAC
1363	TTG	CTC	TTA	TTG	TCT	TCT	TAT	TAT	TGG	TCT	TCT	TCT	TCT
1366	TTT	TTT	TTT	TTT	CAT	CAT	CTT	CTT	GTT	CTC	CTC	CTC	CAT
1417	TAT	TAC	TAC	TAC	–	–	TTC	TTC	TAT	TTC	TTC	TTC	–
1420	CAG	CAA	CAA	CAA	–	–	TCC	TCT	TCA	TCT	TCT	TCT	–
1423	GCC	GCA	GCC	GCT	–	–	CCT	TCT	CCT	CCT	CCT	CCT	–
1450	GAA	ACT	GTT	GAA	–	–	CCT	CCT	ATA	CCT	CCT	CCT	–
1453	GGT	GGT	GGT	GGT	–	–	GCT	GCT	GGT	GCT	GCT	GCT	–
1456	TTT	CTA	CTA	TTT	GAG	GAG	CTT	CCT	CCT	TTT	TTT	TTT	GGT
1459	AAT	AAT	AAT	AAC	AAT	AAT	AAT	AAT	AAT	AAT	AAT	AAT	AAT
1465	TAC	TAC	TAT	TAC	GTC	GTC	TAT	TAT	TAT	TAT	TAT	TAT	GTG
1477	CAA	TAT	GAA	CAA	AGT	AGT	AAT	AGA	CGT	AAT	AAT	AAT	TCA
1486	GGT	GGA	GGT	GGT	GAC	GAC	GGT	GGT	GGC	GGT	GGT	GGT	GAC
1492	CAA	TAC	CAC	CAC	AAC	AAC	TAC	TAC	TTT	TAC	TAC	TAC	AAC
1498	ACT	ACT	ACT	ACT	AAT	AAT	ACT	ACT	ACA	ACT	ACT	ACT	AAC
1501	AAT	GAT	ACA	AAT	GTA	GTA	ACT	AGT	GCT	AAT	AAT	AAT	GTT
1504	GGT	GGT	GGT	GGT	CCG	CCA	GGC	GGC	GGT	GGC	GGC	GGC	CCA
1507	GTT	GTT	GTT	GTT	CTT	CTT	ATT	ATT	GTT	ATA	ATA	ATA	GTA
1513	TAC	CAC	TAC	TAC	TAT	TAC	TAC	TAC	CAC	TAC	TAC	TAC	TAT