Table 1.
Incidence data on AKI in COVID-19 patients
| Author, Journal | Center | Period | Total, n | Population | AKI, n (%) | % RRT | Comorbid conditions |
|---|---|---|---|---|---|---|---|
| China | |||||||
| Chen et al. [11], Lancet | Jinyintan Hospital (Wuhan) | 1–20 January 2020 | 99 | Hospitalized | 3 (3) | 9; 39% in ICU, 0/76 non-ICU | CV disease 40%; DM 12% |
| Yang et al. [12], Lancet Respir Med | Jinyintan Hospital (Wuhan) | December 2019 to 26 January 2020 | 52 | Critically ill | 15 (29)a | 5 | Cardiac disease 10%; DM 17% |
| Zhou et al. [13], Lancet | Jinyintan Hospital and Wuhan Pulmonary Hospital (Wuhan) | Discharged or died by 31 January 2020 | 191 | Hospitalized | 28 (15)a | 5 | HTN 30%; DM 19%; CKD 1% |
| Wang et al. [14], JAMA | Zhongnan Hospital (Wuhan) | 21–30 January 2020 | 138 | Hospitalized | 5 (4)a; 3/36 (8) in ICU, 2/102 (2) non-ICU | 1.5 | HTN 31%; DM 10%; CKD 3% |
| Zhang et al. [15], MedRxiv | Zhongnan Hospital (Wuhan) | 1–10 February 2020 | 221 | Hospitalized | 10 (5)a | 2.3 | HTN 24%; DM 10%; CKD 3% |
| Diao et al. [16], MedRxiv | General Hospital of Theatre Command (Wuhan) | 17 January to 3 March 2020 | 85 | Hospitalized with renal function data | 23 (27) | Not reported | HTN 20%; DM 8%; CKD 6% |
| Cheng et al. [17], Kidney Int | Tongji Hospital (Wuhan) | 28 January to 11 February 2020 | 701 | Hospitalized | 36 (5)a; St.1: 2%, St.2: 1%, St.3: 2% | Not reported | ≥1 comorbidity: 43%; HTN 33%; DM 14%; CKD 2% |
| Wang et al. [8], Am J Nephrol | Renmin Hospital (Wuhan) | 14 January to 13 February 2020 | 116 | Hospitalized | 0a | 0 | HTN 37%; DM 16%; CKD 4% |
| Xiao et al. [18], MedRxiv | Hankou Hospital (Wuhan) | 5 January to 8 March 2020 | 287 | Hospitalized | 55 (19)a; St.1: 14%, St.2/3: 5% | Not reported | HTN 30%; DM 16%; CKD 2% |
| Guan et al. [6], N Engl J Med | 552 Hospitals (30 regions in China) | 11 December 2019 to 29 January 2020 | 1099 | Hospitalized | 6 (0.5)a | 0.8 | HTN 15%; DM 7%; CKD 1% |
| Cao et al. [19], MedRxiv | Shanghai Public Health Clinical Centre (Shanghai) | 20 January to 15 February 2020 | 198 | Hospitalized | 10 (5) | Not reported | HTN 21%; DM 8% |
| Liu et al. [20], Sci China Life Sci | Shenzhen Third People’s Hospital (Shenzhen) | 11–20 January to 3 March 2020 | 12 | Hospitalized | 2 (17) | Not reported | HTN 25%; DM 17%; CKD 17% |
| Wu et al. [21], Clin Infect Dis | 3 Hospitals (Jiangsu Province) | 22 January to 14 February 2020 | 80 | Hospitalized | 2 (2.5) | 1 | CV disease 31%; CKD 1% |
| Yang et al. [22], J Infect | 3 Hospitals (Wenzhou) | 17 January to 10 February 2020 | 149 | Hospitalized | 0 | Not reported | CV disease 19% |
| Outside China | |||||||
| Arentz et al. [23], JAMA | Evergreen Hospital (Seattle, USA) | 20 February to 5 March 2020 | 21 | Critically ill | 4 (19); defined as need for KRT | 4 (19) | ≥1 comorbidity: 86%; CKD 48%; ESKD 10% |
| ICNARC [24] | All ICUs (England, Wales, Northern Ireland; UK) | Until 8 May 2020 | 8250 | Critically ill | 1442 (17); defined as need for KRT | 1442 (17) | CV disease 0.4%; CKD 1.4% |
| Chan et al. [1], MedRxiv | Mount Sinai Hospital (New York, USA) | 27 February to 15 April 2020 | 3235 | Hospitalized | 1406 (43)a; 68% in ICU | 280 (20) | HTN 37%; DM 25%; CKD 10% |
| Hirsch et al. [25], Kidney Int | Northwell Health Hospital (New York, USA) | 1 March to 5 April 2020 | 5449 | Hospitalized | 1993 (37)a; St.1: 17%, St.2: 8%, St.3: 12% | 285 (5) | HTN 79%; DM 48%; Mean BMI 29 |
| Mohamed et al. [26], Kidney 360 | Ochsner Health Hospital (New Orleans, USA) | March 2020 | 575 | Hospitalized | 161 (28)a; 61% in ICU, 14% in non-ICU | 89 (15) | HTN 72%; DM 48%; CKD 29% |
| Argenziano et al. [27], BMJ | New York-Presbyterian / Columbia University Irving Medical Center (New York, USA) | 1 March to 5 April 2020 | 850 | Hospitalized | 288 (34); 78% in ICU | 117 (14); 35% in ICU | HTN 60%; DM 37%; CKD 14% |
a
KDIGO criteria used for defining AKI. Studies were not included which were clearly from same institution and period of time (to avoid double counting); however, the data from the first three studies from Jinyintan Hospital likely still does represent overlapping data. Source: http://www.nephjc.com/news/covidaki BMI, body mass index; DM, diabetes mellitus; ESKD, end-stage kidney disease; HTN, hypertension.