Table 1.
Unadjusted and Adjusted Relative Hazards of Adjunctive Corticosteroids on Clinical Progression and Invasive Mechanical Ventilationa
| Outcome | N | Unadjusted Analysis HR (95% CI) | P Value | Adjusted Analysis HR (95% CI) | P Value |
|---|---|---|---|---|---|
| Clinical Progression | |||||
| Overall | 92 | 0.46 (0.15–1.40) | .169 | 0.08 (0.01–0.99) | .049 |
| Pneumonia | 44 | 0.13 (0.04–0.48) | .002 | 0.15 (0.06–0.39) | <.001 |
| Invasive Mechanical Ventilation | |||||
| Overall | 92 | 0.88 (0.26–3.02) | .844 | 0.22 (0.02–2.54) | .22 |
| Pneumonia | 44 | 0.22 (0.06–0.85) | .028 | 0.30 (0.10–0.87) | .029 |
Abbreviations: CI, confidence interval; HR, hazard ratio; N, number.
aCovariates in adjusted analysis were age, gender, body mass index, comorbidity, clinical stage, antibiotic use, C-reactive protein, procalcitonin, lymphocyte count, neutrophils-lymphocyte ratio and creatinine. Clinical progression, progression to requiring supplemental oxygen in Stage 1 and 2, or progression to invasive mechanical ventilation in any stage.