Table 2.

Associations Between Schizophrenia, In-Hospital Mortality, and ICU Admission (n = 50 750)

	In-Hospital Mortality		ICU Admission
	OR (95% CI)	P value	OR (95% CI)	P value
Model 1	1.246 (1.045–1.485)	.0186	0.782 (0.653–0.937)	.0118
Model 2	1.298 (1.080–1.561)	.0093	0.749 (0.619–0.906)	.0062
Model 3
Interaction term, age × SCZ		.0006*		<.0001*
<55 years	1.761 (0.912–3.401)	.0905	1.582 (1.087–2.299)	.0177
55–65 years	1.577 (0.969–2.571)	.0661	0.919 (0.630–1.340)	.6561
65–80 years	1.621 (1.276–2.062)	.0002	0.533 (0.405–0.702)	<.001
≥80 years	0.873 (0.657–1.161)	.3429	0.509 (0.294–0.880)	.0168
Interaction term, geographical areas of hospitalization × SCZ		.0797*		.0591*

Note: Model 1: unadjusted model. Model 2: adjustment for sociodemographic data (age, sex, social deprivation), clinical data at baseline (smoking status, overweight and obesity, Charlson Comorbidity Index), stay data (origin of the patient), hospital data (hospital category, number of hospital stays for COVID-19), and geographical areas of hospitalization. Model 3: model 2 plus the interaction term age × SCZ. There was no heterogeneity in the interaction between SCZ and geographical areas of hospitalization. P value in bold denotes statistical significance. Reference: controls. ICU, intensive care unit; SCZ, schizophrenia.

*P value for interaction.