Table 2.
Modeled Prevalence, Sensitivity, Specificity, and Positive Predictive Value Based on Independent and Conjoined Antibody Testing Results
| Test Characteristics | Estimate and 95% CrI |
|---|---|
| Prevalence | |
| Using Abbott only | 0.29% (0.01%–0.78%) |
| Using ELISA only | 0.23% (0.01%–0.62%) |
| Using Abbott and ELISA | 0.16% (0.02%–0.46%) |
| Sensitivity | |
| Abbott assay (independent) | 99.61% (97.98%–99.99%) |
| ELISA assay (independent) | 96.25% (89.36%–99.51%) |
| Abbott assay, using both | 99.60% (98.00%–99.99%) |
| ELISA assay, using both | 96.23% (89.45%–99.52%) |
| Specificity | |
| Abbott assay (independent) | 99.68% (99.37%–99.88%) |
| ELISA assay (independent) | 99.88% (99.58%–100%) |
| Abbott assay, using both | 99.61% (99.32%–99.82%) |
| ELISA assay, using both | 99.83% (99.56%–99.97%) |
| Positive Predictive Value | |
| Abbott + (independent) | 44.19% (3.25%–83.06%) |
| ELISA + (independent) | 63.32% (5.46%–98.64%) |
| Abbott + and ELISA + | 99.11% (95.75%–99.94%) |
| Abbott + and ELISA – | 1.67% (0.07%–7.47%) |
| Abbott – and ELISA + | 0.56% (0%–3.48%) |
Abbreviations: CrI, credible interval; ELISA, enzyme-linked immunosorbent assay.