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. 2020 Nov 13;15(11):e0241999. doi: 10.1371/journal.pone.0241999

Table 4. Risk factors associated to HIV/syphilis co-infection among pregnant women aged beyond 15 years old who were tested for HIV and syphilis, national sentinel surveillance survey of HIV and syphilis 2017.

Characteristics Univariate Analysis Multivariate Analysis
HIV/syphilis Co-infection vs No infection HIV infection vs No infection Syphilis infection vs No infection HIV/syphilis Co-infection vs No infection HIV infection vs No infection Syphilis infection vs No infection
OR [95% IC] OR [95% IC] OR [95% IC] aOR [95% IC] aOR [95% IC] aOR [95% IC]
Residence
 Urban Ref Ref Ref* Ref Ref Ref
 Rural 1 [0.4–2.5 ] 0.8 [0.7–1.1 ] 1.9 [1.4–2.5 ] 1.1 [0.4–2.8 ] 0.9 [0.7–1.1 ] 1.8 [1.3–2.4 ] μ
Region Group
Northern 0.3 [0.1–1.4 ] 0.6 [0.4–0.8 ] 0.6 [0.4–0.9 ] 0.5 [0.1–2.1 ] 0.6 [0.5–0.9 ] μ 0.6 [0.4–0.9 ] μ
Southern Ref Ref Ref* Ref Ref Ref
Type of union
 Single 2.5 [1–6.4 ] 1.1 [0.8–1.4 ] 1.1 [0.8–1.5 ] 2.9 [1–8.2 ] a 1.5 [1.1–2.1 ] μ 1 [0.7–1.5 ]
 Married/Cohabiting/Widow/Divorced Ref Ref Ref* Ref Ref Ref
Education
 None Ref Ref Ref*
 Primary 0.7 [0.1–3 ] 2.1 [1.3–3.3 ] 1.8 [1.1–3.1 ]
 Secondary 0.5 [0.1–1.9 ] 1.4 [0.9–2.3 ] 1.2 [0.7–2 ]
 Higher 1.2 [0.3–5.4 ] 1.1 [0.6–2 ] 0.8 [0.4–1.5 ]
Primiparous
 Yes Ref Ref Ref* Ref Ref Ref
 No 0.9 [0.3–2.6 ] 3 [2.1–4.5 ] 0.9 [0.6–1.2 ] 0.4 [0.1–1.2 ] 2.7 [1.7–4.3 ] μ 1 [0.7–1.4 ]
Number of pregnancies
 0 Ref Ref Ref*
 2 to 3 0.1 [0–1.1 ] 2.6 [1.7–4 ] 0.8 [0.6–1.2 ]
 4 to 5 1.8 [0.6–5.5 ] 3.8 [2.5–5.8 ] 0.9 [0.6–1.3 ]
 >5 1.7 [0.5–6 ] 3.1 [1.9–4.9 ] 1.2 [0.7–1.8 ]
Age (in years)
 15–24 Ref Ref Ref* Ref Ref Ref*
 25–49 7.2 [1.7–31.2 ] 2.4 [1.9–3.2 ] 0.8 [0.6–1.1 ] 15.1 [3–75.7 ]μ 2 [1.4–2.6 ] μ 0.8 [0.6–1.2 ]
Occupation
 Housewife Ref Ref Ref*
 Student 0.6 [0.1–2.6 ] 0.4 [0.3–0.6 ] 1.3 [0.8–1.8 ]
 Formal employee (Civil servant) 0.7 [0.1–5.4 ] 1.2 [0.7–1.8 ] 0.9 [0.5–1.6 ]
 Informal employee/entrepreneurship 1.5 [0.5–4.3 ] 1.6 [1.2–2.2 ] 1.4 [12 ]
 Unemployed & Others 0.9 [0.1–7.4 ] 1.3 [0.8–2.1 ] 1.5 [0.8–2.6 ]

a: attempted a borderline.

Ref: reference category

#: Global p-value < 0.25

*: Global p-value < 0.05

μ: P-value < 0.05