Table 4. Cutoffs for Fungal Infection (N = 457).
| Variable | Best cutoffa | Sensitivityb | Specificityb | Youdenc |
|---|---|---|---|---|
| MELD | 19.33 | 81.8% | 58.6% | 40.4% |
| Total bilirubin | 4.20 | 64.0% | 67.8% | 31.8% |
| International normalized ratio | 1.50 | 79.2% | 54.8% | 33.9% |
| Hemoglobin | 11.30 | 76.0% | 49.8% | 25.8% |
aThe value maximizes Youden statistic. bROC analysis was performed to derive sensitivity and specificity based on a logistic regression model with the continuous variable of interest (e.g., MELD) as the only covariate. cYouden = sensitivity + specificity - 1. MELD: model for end-stage liver disease; ROC: receiver operating characteristic.