Table 4. Strength of Evidence.

Author	Hb	Transfusion rate	Significant AE	QOL	Infections	LOS	Mortality
Cladellas et al, 2012 [32]	X	X	X		X	X	X
Urena et al, 2017 [34]	X	X	X		X	X	X
Johansson et al, 2015 [36]	X	X	X		X		X
Padmanabhan et al, 2018 [35]	X	X	X	X	X	X	X
Garrido-Martin et al, 2012 [33]	X	X	X		X
Spahn et al, 2019 [37]	X	X	X		X	X	X
Summary of Level of Evidencea	(6) 1b	(6) 1b	(6) 1b	(1) 2b	(6) 1b	(4) 1b	(5) 1b
Quality of Body of Evidenceb	Moderate	Moderate	Moderate	Low	Moderate	Moderate	Moderate

^aOxford Centre for Evidence-based Medicine’s “Levels of Evidence.” https://www.cebm.net/2009/06/oxford-centre-evidence-based-medicine-levels-evidence-march-2009/; ^bCincinnati Children’s Hospital Medical Center Evidence Collaboration’s, file:///Users/kellytankard/Downloads/Guideline%20Development%20Manual%20(1).pdf. AE: adverse event; Hb: hemoglobin; QOL: quality of life; LOS: length of stay.