Table 3. Logistic Regression Analysis for a Large IAD-eGFR More Than 10% of Among Pretreatment Factors.
| Baseline variable | Univariate logistic regression |
Multivariate logistic regression using forced inclusion model |
||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P | OR | 95% CI | P | |
| Age (per 1.0; year) | 0.977 | 0.933 - 1.022 | 0.308 | |||
| Gender (male) | 0.488 | 0.183 - 1.300 | 0.151 | |||
| Body mass index (per 1.0) | 0.994 | 0.887 - 1.114 | 0.920 | |||
| Body weight (per 1.0; kg) | 0.980 | 0.944 - 1.018 | 0.980 | |||
| Hypertension (yes) | 1.196 | 0.267 - 5.356 | 0.815 | |||
| Dyslipidemia (yes) | 1.848 | 0.338 - 10.102 | 0.479 | |||
| Current smoker (yes) | 1.297 | 0.424 - 3.970 | 0.648 | |||
| CVD history (yes) | 0.909 | 0.380 - 2.174 | 0.830 | |||
| DM retinopathy (yes) | 1.237 | 0.514 - 2.984 | 0.634 | |||
| HbA1c (per 1.0; %) | 1.001 | 0.967 - 1.037 | 0.945 | |||
| Duration of DM (per 1.0; years) | 1.029 | 0.984 - 1.078 | 0.229 | |||
| Insulin therapy (yes) | 1.867 | 0.760 - 4.584 | 0.173 | |||
| eGFR (per 1.0; mL/min/1.73 m2) | 0.953 | 0.867 - 1.048 | 0.320 | |||
| Presence of proteinuria (yes) | 2.567 | 1.068 - 6.168 | 0.035 | 1.789 | 0.539 - 5.945 | 0.342 |
| Presence of hematuria (yes) | 1.682 | 0.677 - 4.176 | 0.263 | |||
| Annual eGFR decline (per 1.0; %) | 0.920 | 0.844 - 1.002 | 0.054 | |||
| ACEi or ARB treatment (yes) | 1.500 | 0.578 - 3.890 | 0.404 | |||
| Diuretics treatment (yes) | 1.837 | 0.719 - 4.696 | 0.204 | |||
| Systolic BP (per 1.0; mmHg) | 0.994 | 0.964 - 1.025 | 0.699 | |||
| Estimated daily salt intake (per 1.0; g/day) | 1.324 | 1.062 - 1.649 | 0.013 | 1.334 | 1.023 - 1.738 | 0.033 |
| Body-fat percentage (per 1.0; %) | 0.982 | 0.926 - 1.040 | 0.530 | |||
| Percent of ToBW to weight (per 1.0; %) | 1.023 | 0.948 - 1.105 | 0.554 | |||
| Percent of ECW to ToBW (per 1.0; %) | 1.879 | 1.059 - 3.333 | 0.031 | 1.152 | 0.587 - 2.262 | 0.680 |
| Serum albumin (per 0.1; mg/dL) | 0.878 | 0.775 - 0.995 | 0.042 | 0.874 | 0.724 - 1.056 | 0.162 |
| Hb (per 1.0; g/dL) | 0.655 | 0.469 - 0.916 | 0.013 | 0.656 | 0.409 - 1.050 | 0.079 |
| Urinary specific gravity (per 0.001) | 0.948 | 0.888 - 1.012 | 0.108 | |||
OR: odds ratio; CI: confidence interval; CVD: cerebro-cardio vascular disease; DM: diabetes mellitus; Hb: hemoglobin; eGFR: estimated glomerular filtration rate; ACEi, angiotensin converting enzyme inhibitor; ARB: angiotensin-II receptor blocker; BP: blood pressure; ToBW: total body water; ECW: extracellular water; Hosmer-Lemeshow test showed P = 0.87 in multivariate analysis.