Table 2:
Selected ABS methods using oxidative organic reactions (B).[a]
Primary Reaction | Associated Secondary Reactions |
Analytes | Associated Imaging Modalities |
Seminal Refs./Reviews |
---|---|---|---|---|
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(formal) retro [2+2] cycloaddition | 1O2 | chemiluminescence | 116 |
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Criegee fragmentation, b-elimination | O3 | fluorescence | 117 |
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dehydration | NO+O2 | fluorescence | 65 |
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dehydration, electrophilic aromatic substitution | NO+O2 | fluorescence | 118 |
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5-exo-tet cyclization, hydrolysis | ONOO− | fluorescence | 120, 121 |
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5-exo-trig cyclization, trans-esterification | HNO | fluorescence | 123 |
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dehydration, 5-exo-trig cyclization | HNO | fluorescence, chemiluminescence | 124 |
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5-exo-trig cyclization, thio-esterification | RS-(S)n-SR, H2S2, or S8 | fluorescence | 128 |
HSnR (n>1); RSH, S8 | 129 |
EDG = electron-donating group.