Table 6.
Absolute organ weights of rats treated with sericin extract for 90 days.
| Dose (mg/kg) | Liver | Kidneys | Spleen | Testes/ovaries | Brain | Heart | Thymus | Adrenal | Epididymis/uterus |
|---|---|---|---|---|---|---|---|---|---|
| Male | |||||||||
| 1000 | 13.83 ± 1.08 | 3.532 ± 0.229 | 0.939 ± 0.050 | 3.715 ± 0.309 | 2.168 ± 0.066 | 1.561 ± 0.104 | 0.590 ± 0.078 | 0.085 ± 0.016 | 1.348 ± 0.112 |
| 500 | 13.54 ± 0.99 | 3.479 ± 0.266 | 0.946 ± 0.074 | 3.673 ± 0.253 | 2.164 ± 0.078 | 1.627 ± 0.124 | 0.540 ± 0.067 | 0.083 ± 0.013 | 1.431 ± 0.120 |
| 250 | 14.05 ± 1.98 | 3.599 ± 0.504 | 0.961 ± 0.098 | 3.728 ± 0.401 | 2.099 ± 0.075 | 1.663 ± 0.200 | 0.591 ± 0.074 | 0.090 ± 0.026 | 1.389 ± 0.185 |
| Control | 13.92 ± 1.36 | 3.573 ± 0.243 | 0.925 ± 0.094 | 3.742 ± 0.155 | 2.085 ± 0.098 | 1.639 ± 0.129 | 0.541 ± 0.068 | 0.084 ± 0.016 | 1.446 ± 0.175 |
|
| |||||||||
| Female | |||||||||
| 1000 | 7.74 ± 0.89 | 1.873 ± 0.135 | 0.555 ± 0.075 | 0.158 ± 0.023 | 1.899 ± 0.046 | 1.015 ± 0.084 | 0.433 ± 0.051 | 0.075 ± 0.015 | 0.594 ± 0.064 |
| 500 | 7.56 ± 0.45 | 1.909 ± 0.121 | 0.597 ± 0.052 | 0.159 ± 0.015 | 1.967 ± 0.079 | 1.005 ± 0.101 | 0.477 ± 0.057 | 0.072 ± 0.010 | 0.657 ± 0.077 |
| 250 | 7.93 ± 1.16 | 1.883 ± 0.173 | 0.559 ± 0.046 | 0.159 ± 0.029 | 1.896 ± 0.094 | 1.006 ± 0.064 | 0.458 ± 0.053 | 0.076 ± 0.013 | 0.609 ± 0.065 |
| Control | 7.96 ± 1.08 | 1.965 ± 0.350 | 0.571 ± 0.055 | 0.155 ± 0.018 | 1.890 ± 0.070 | 0.999 ± 0.148 | 0.455 ± 0.085 | 0.073 ± 0.012 | 0.624 ± 0.091 |
Note: The values represent the mean ± standard deviation of 10 rats. The values of the treatment groups did not differ statistically from the control according to one-way ANOVA at p < 0.05.