Table 7.
Relative organ weights of rats treated with sericin extract for 90 days.
| Dose (mg/kg) | Liver | Kidneys | Spleen | Testes/ovaries | Brain | Heart | Thymus | Adrenal | Epididymis/uterus |
|---|---|---|---|---|---|---|---|---|---|
| Male | |||||||||
| 1000 | 2.562 ± 0.173 | 0.655 ± 0.051 | 0.174 ± 0.011 | 0.689 ± 0.057 | 0.402 ± 0.019 | 0.289 ± 0.018 | 0.109 ± 0.010 | 0.016 ± 0.002 | 0.250 ± 0.026 |
| 500 | 2.475 ± 0.118 | 0.636 ± 0.039 | 0.173 ± 0.016 | 0.673 ± 0.048 | 0.397 ± 0.023 | 0.298 ± 0.021 | 0.098 ± 0.009 | 0.015 ± 0.002 | 0.263 ± 0.030 |
| 250 | 2.488 ± 0.149 | 0.638 ± 0.052 | 0.171 ± 0.009 | 0.663 ± 0.045 | 0.375 ± 0.025 | 0.296 ± 0.026 | 0.105 ± 0.010 | 0.016 ± 0.004 | 0.247 ± 0.026 |
| Control | 2.531 ± 0.133 | 0.652 ± 0.051 | 0.169 ± 0.016 | 0.684 ± 0.058 | 0.380 ± 0.018 | 0.299 ± 0.021 | 0.098 ± 0.010 | 0.015 ± 0.003 | 0.264 ± 0.036 |
|
| |||||||||
| Female | |||||||||
| 1000 | 2.696 ± 0.164 | 0.654 ± 0.041 | 0.193 ± 0.021 | 0.055 ± 0.009 | 0.665 ± 0.042 | 0.355 ± 0.031 | 0.151 ± 0.018 | 0.026 ± 0.004 | 0.208 ± 0.025 |
| 500 | 2.534 ± 0.157 | 0.640 ± 0.046 | 0.201 ± 0.021 | 0.054 ± 0.008 | 0.661 ± 0.053 | 0.337 ± 0.033 | 0.160 ± 0.016 | 0.024 ± 0.004 | 0.221 ± 0.030 |
| 250 | 2.688 ± 0.189 | 0.641 ± 0.040 | 0.191 ± 0.019 | 0.054 ± 0.007 | 0.648 ± 0.054 | 0.344 ± 0.03 | 0.156 ± 0.019 | 0.026 ± 0.004 | 0.209 ± 0.034 |
| Control | 2.694 ± 0.121 | 0.663 ± 0.056 | 0.195 ± 0.018 | 0.053 ± 0.008 | 0.646 ± 0.051 | 0.340 ± 0.038 | 0.154 ± 0.022 | 0.025 ± 0.003 | 0.213 ± 0.035 |
Note: The values represent the mean ± standard deviation of 10 rats. Relative organ weight (%) = (absolute organ weight/fasting body weight) × 100%. The values of the treatment groups did not differ statistically from the control according to one-way ANOVA at p < 0.05.