Table 2:
Predicted percentage of patients with adenomas detected, referred to colonoscopy, and with cancer detected at screening via flexible sigmoidoscopy or colonoscopy. All estimates are expressed with a point estimate and 95% credible or confidence intervals.
| Outcome | Source | Percent |
|---|---|---|
| Adenomas Detected at Flexible Sigmoidoscopy (‘distal’ location) (Percentage of Patients) |
||
| CRC-SPIN2.0 | 14.4 (14.0, 14.7) | |
| CRC-SPIN1.0 | 9.4 (9.2, 9.7) | |
| MISCAN | 27.7 (27.2, 28.2) | |
| SimCRC | 8.8 (8.5, 9.0) | |
| UKFSS | 12.1 (11.8, 12.4) | |
| Referred to Colonoscopy (Percentage of Patients) | ||
| CRC-SPIN2.0 | 6.5 (6.3, 6.8) | |
| CRC-SPIN1.0 | 3.6 (3.4, 3.8) | |
| MISCAN | 13.6 (13.3, 14.0) | |
| SimCRC | 4.0 (3.8, 4.2) | |
| UKFSS | 5.2 (4.3, 6.2) | |
| Among Patients with Colonoscopy, the Percentage with Adenomas Detected* | ||
| CRC-SPIN2.0 | 59.2 (57.3, 61.2) | |
| CRC-SPIN1.0 | 39.1 (36.7, 41.7) | |
| MISCAN | 73.0 (71.8, 74.1) | |
| SimCRC | 35.6 (33.3, 37.9) | |
| UKFSS | 18.8 (17.1, 20.5) | |
| Percentage of Patients with Screen Detected CRC | ||
| CRC-SPIN2.0 | 0.34 (0.28, 0.40) | |
| CRC-SPIN1.0 | 0.11 (0.08, 0.15) | |
| MISCAN | 0.45 (0.39, 0.52) | |
| SimCRC | 0.44 (0.38, 0.51) | |
| UKFSS | 0.34 (0.29, 0.40) |
*
These adenomas have a proximal location