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. Author manuscript; available in PMC: 2021 Sep 1.
Published in final edited form as: J Am Geriatr Soc. 2020 May 13;68(9):2034–2042. doi: 10.1111/jgs.16522

Table 2.

Association of Frailty Phenotype with Total Healthcare Costs

Total healthcare costs
Frailty phenotype Cost ratio (95% CI) P
Base modela
 Robust 1.00 (referent) <0.001
 Pre-frail 1.42 (1.23-1.64)
 Frail 2.72 (2.19-3.37)
Multivariable (MV) modelb
 Robust 1.00 (referent) <0.001
 Pre-frail 1.28 (1.11-1.48)
 Frail 2.35 (1.88-2.93)
MV model + functional limitationsc
 Robust 1.00 (referent) <0.001
 Pre-frail 1.20 (1.04-1.38)
 Frail 1.99 (1.56-2.52)
MV model + Kim CFI
 Robust 1.00 (referent) <0.001
 Pre-frail 1.23 (1.07-1.42)
 Frail 2.07 (1.65-2.60)
MV model + functional limitations + Kim CFI
 Robust 1.00 (referent) <0.001
 Pre-frail 1.18 (1.02-1.36)
 Frail 1.87 (1.47-2.39)

Note: CFI, claims-based frailty index

a

adjusted for age, race, and site

b

adjusted for age, race, site, multimorbidity burden, and cognitive function

c

functional limitations defined by number of IADL impairments