Table 1.

Selected characteristics and findings in three trials that evaluated intensive blood pressure lowering in stroke survivors.

					Intensive Therapy			Standard Therapy
Trial	Sample size	Mean Age, y	Follow-up, y	Primary outcome	Target BP	Achieved BP	Stroke events	Target BP	Achieved BP	Stroke events
SPS3 [17]	3020	63	3.7	Stroke	<130	12/7	125	130-149	138	152
RESPECT [18]	1263	67	3.9	Stroke	<120/80	127/77	39	<140/90	133/78	52
PAST-BP [19]	83	72	1.0	BP	<130*	127/72	0	<140	129/74	3
PODCAST [20]	83	74	2.0	Cognitive function	<125	130/73†	1	<140	140/77†	3
					Total strokes		165	Total strokes		210

SPS3=Secondary Prevention of Small Cortical Strokes; RESPECT=Recurrent Stroke Prevention Clinical Outcome; PAST-BP=Prevention After Stroke-Blood Pressure.

^*or SBP reduction >10 mm Hg if starting SBP was <140 mm Hg.

^**at the six-month visit