Superimposition modeling image of 107 (green) and 111 (orange). Reproduced with permission from Bioorganic & Medicinal Chemistry Letters (https://www.sciencedirect.com/journalbioorganic-and-medicinal-chemistry-letters/), Volume 21, pp 506–509, Morrison, A. J.; Adam, J. M.; Baker, J. A.; Campbell, R. A.; Clark, J. K.; Cottney, J. E.; Deehan, M.; Easson, A. M.; Fields, R.; Francis, S.; Jeremiah, F.; Keddie, N.; Kiyoi, T.; McArthur, D. R.; Meyer, K.; Ratcliffe, P. D.; Schulz, J.; Wishart, G.; Yoshiizumi, K., Design, synthesis, and structure-activity relationships of indole-3-heterocycles as agonists of the CB1 receptor.161 Copyright 2011 Elsevier.