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. Author manuscript; available in PMC: 2021 Nov 12.
Published in final edited form as: J Med Chem. 2020 Aug 4;63(21):12290–12358. doi: 10.1021/acs.jmedchem.0c00530

Figure 37.

Figure 37.

Compound 139 docked within the active site of AKR1C3 (gray, PDB code 3UG8): strong predicted hydrogen bond (green dotted line) and weak predicted hydrogen bond (white dotted line). Reproduced with permission from Journal of Medicinal Chemistry,183 Copyright 2019 American Chemical Society.