a) Relative infectivity of cells expressing paRTP4, hsRTP4, hsIRF1, or an empty vector. Heatmap cells represent the mean of N = 3 biological replicates, normalized to control. Raw infectivity and experimental details: Supplemental Figure 2.
b) HCV-GLuc infection of Huh7.5 cells expressing paRTP4, hsRTP4, or a vector control. Points indicate the mean ± SD Relative Light Units (RLU) of N = 3 biological replicates. RM ANOVA on log-transformed data with Holm-Sidak test.
c) Huh7.5 cells expressing paRTP4, hsRTP4, hsIRF1, or vector control were transfected with YFRluc2a replicon RNA. Bars: mean ± SD RLU of N = 3 biological replicates. Two-way ANOVA on log-transformed data with Holm-Sidak test.