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. Author manuscript; available in PMC: 2021 Nov 12.
Published in final edited form as: J Med Chem. 2020 Sep 10;63(21):12137–12155. doi: 10.1021/acs.jmedchem.0c00724

Table 3.

Average CBD dose, Tmax, and Cmax for human studies of CBD administration.

Avg dose (mg) Avg Tmax (hr) Avg Cmax (ng/mL) Avg Cmax (nM) %F (if reported)
Low oral dosea 14 ± 15 1.9 ± 1.2 2.8 ± 2.2 0.9
High oral doseb 525 ± 340 3.1 ± 0.3 131.9 ± 82.5 41.5
Inhalation dosec 3.5 ± 5.5 0.3 ± 0.3 35.3 ± 41.3 11.1 31%

Analysis of 50 reported studies of CBD dosing that included reported plasma levels.

a

Dose range: 1.5–20 mg

b

Dose range: 100–800 mg

c

Dose range: 1.5–20 mg