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. Author manuscript; available in PMC: 2021 Apr 28.
Published in final edited form as: Nature. 2020 Oct 28;587(7833):258–263. doi: 10.1038/s41586-020-2860-1

Extended Data Figure 10. Summary of two parallel ascending SPB pathways and a phylogenetic tree of structurally-related GPCR family proteins.

Extended Data Figure 10.

a, Summary cartoon of two parallel ascending SPB pathways for affective touch and pain. b, A phylogenetic tree generated using a multiple sequence alignment algorithm, ClustalW2 (EMBL-EBI). The top 14 mouse proteins that have the highest amino acid sequence similarity to mouse GPR83 were used for this analysis.