Table 1.
Summary of demographic, genetic, and lifestyle risk information of CARDS participants.
Mean (SD) (range) | |
---|---|
Sample size n | 165 |
Age (in years) | 55.7 (8.2) (38–71) |
Females | 57% |
NART-IQ | 116.8 (6.7) (96–128) |
MMSE | 29.1 (0.9) (27–30) |
FH + | 35.8% |
APOE4 + | 38.8% |
WHR | 1.4 (0.5) (0.7–2.2) |
Systolic BP (mm Hg) | 132 (18.8) (68.3–196) |
Diastolic BP (mm Hg) | 83.3 (9.4) (58.7–118.7) |
Smokers | 5.5% |
Diabetes | 1.8% |
Alcohol units per week | 7.4 (9.4) (0–60) |
PHQ-9 Depression score | 2.6 (2.9) (0–13) |
APOE = Apolipoprotein-E based on DNA extraction and APOE genotyping of saliva samples using TaqMan genotyping of single nucleotide polymorphism (SNP) rs7412 and KASP genotyping of SNP rs429358. FH = Family History of a first degree relative affected by Alzheimer’s or Lewy body disease or vascular dementia. MMSE = Mini Mental State Exam (maximum score = 30)42, NART-IQ = National Adult Reading Test- Intelligence Quotient66, PHQ-9 = Patient Health Questionnaire (maximum score = 27)109. WHR = Waist-to-Hip-Ratio.