. 2020 Nov 13;10:19787. doi: 10.1038/s41598-020-75992-9

Table 3.

Post-hoc effects of APOE genotype and sex on the macromolecular proton fraction (MPF).

Effect	Side	ROI	F_(1,123)-value	p_BHadj
APOE	Left	Accumbens	3.985	0.214
		Amygdala	0.171	0.869
		Caudate	6.710	0.090
		Hippocampus	5.327	0.143
		Pallidum	0.099	0.891
		Putamen	1.416	0.511
		Thalamus	10.772	0.026
	Right	Accumbens	0.310	0.790
		Amygdala	0.125	0.868
		Caudate	3.433	0.264
		Hippocampus	6.700	0.095
		Pallidum	0.039	0.919
		Putamen	1.226	0.561
		Thalamus	5.233	0.144
	Left	Banks of superior temporal sulcus	3.424	0.261
		Caudal anterior cingulate	1.518	0.483
		Cuneus	0.631	0.689
		Entorhinal	0.002	0.986
		Frontal pole	2.579	0.320
		Fusiform	0.771	0.669
		Inferior parietal	0.886	0.631
		Inferior temporal	0.942	0.635
		Insula	6.754	0.097
		Lateral occipital	0.307	0.788
		Lateral orbito frontal	0.355	0.777
		Lingual	0.641	0.690
		Medial orbito frontal	0.001	0.993
		Middle temporal	2.653	0.318
		Paracentral	0.035	0.924
		Parahippocampal	0.150	0.865
		Pars opercularis	8.341	0.097
		Pars orbitalis	0.028	0.932
		Pars triangularis	0.019	0.945
		Postcentral	2.459	0.331
		Posterior cingulate	1.065	0.592
		Precentral	3.040	0.297
		Precuneus	0.000	0.997
		Rostral anterior cingulate	0.531	0.714
		Rostral middle frontal	0.112	0.880
		Superior frontal	0.515	0.719
		Superior parietal	0.222	0.836
		Superior temporal	1.096	0.594
		Supramarginal	2.657	0.312
		Temporal pole	3.597	0.252
		Transverse temporal	5.752	0.117
	Right	Banks of superior temporal sulcus	0.085	0.892
		Caudal anterior cingulate	6.693	0.100
		Cuneus	0.077	0.897
		Entorhinal	0.088	0.892
		Frontal pole	0.070	0.882
		Fusiform	2.047	0.416
		Inferior parietal	0.736	0.673
		Inferior temporal	0.162	0.865
		Insula	4.235	0.198
		Isthmus cingulate	0.927	0.635
		Lateral occipital	0.072	0.891
		Lateral orbito frontal	0.785	0.668
		Lingual	3.499	0.262
		Medial orbito frontal	1.979	0.407
		Middle temporal	0.130	0.876
		Paracentral	0.071	0.887
		Parahippocampal	1.994	0.409
		Pars opercularis	1.551	0.493
		Pars orbitalis	0.511	0.714
Pars triangularis		0.001	0.986
Pericalcerine		0.875	0.629
Postcentral		0.074	0.895
Posterior cingulate		1.341	0.532
Precentral		0.303	0.784
Precuneus		0.198	0.854
Rostral anterior cingulate		1.850	0.429
Rostral middle frontal		0.151	0.858
Superior frontal		0.026	0.932
Superior parietal		1.548	0.488
Superior temporal		1.148	0.579
Supramarginal		0.167	0.866
Temporal pole		0.764	0.665
Transverse temporal		0.155	0.867
Sex	Left	Accumbens	0.353	0.784
		Amygdala	0.014	0.956
		Caudate	1.918	0.418
		Hippocampus	0.684	0.673
		Pallidum	1.079	0.594
		Putamen	2.12	0.405
		Thalamus	2.668	0.321
	Right	Accumbens	0.126	0.874
		Amygdala	0.000	0.993
		Caudate	0.046	0.912
		Hippocampus	0.223	0.842
		Pallidum	0.697	0.673
		Putamen	2.678	0.324
		Thalamus	0.571	0.710
	Left	Banks of superior temporal sulcus	0.559	0.711
		Caudal anterior cingulate	0.459	0.742
		Cuneus	7.712	0.093
		Entorhinal	5.902	0.115
		Frontal pole	4.243	0.204
		Fusiform	0.007	0.971
		Inferior parietal	6.242	0.104
		Inferior temporal	0.191	0.854
		Insula	1.298	0.541
		Lateral occipital	0.063	0.888
		Lateral orbito frontal	0.002	0.992
		Lingual	3.095	0.293
		Medial orbito frontal	2.921	0.298
		Middle temporal	2.496	0.331
		Paracentral	0.009	0.968
		Parahippocampal	7.180	0.104
		Pars opercularis	1.169	0.578
		Pars orbitalis	1.524	0.488
		Pars triangularis	7.929	0.085
		Postcentral	0.903	0.638
		Posterior cingulate	15.379	< 0.001
		Precentral	0.726	0.664
		Precuneus	4.327	0.201
		Rostral anterior cingulate	0.727	0.669
		Rostral middle frontal	18.725	< 0.001
		Superior frontal	4.349	0.202
		Superior parietal	1.629	0.474
		Superior temporal	13.584	< 0.001
		Supramarginal	7.837	0.104
		Temporal pole	3.766	0.238
		Transverse temporal	7.374	0.096
	Right	BANKS of superior temporal sulcus	2.881	0.292
		Caudal anterior cingulate	4.038	0.215
		Cuneus	7.177	0.089
		Entorhinal	2.004	0.413
		Frontal pole	4.610	0.196
		Fusiform	0.097	0.886
		Inferior parietal	1.757	0.442
		Inferior temporal	0.352	0.771
		Insula	2.943	0.308
		Isthmus cingulate	0.443	0.746
		Lateral occipital	0.297	0.782
		Lateral orbito frontal	0.356	0.790
		Lingual	3.196	0.289
		Medial orbito frontal	4.570	0.195
		Middle temporal	0.360	0.793
		Paracentral	0.425	0.752
		Parahippocampal	0.975	0.625
		Pars opercularis	0.340	0.774
		Pars orbitalis	0.892	0.636
Pars triangularis		6.046	0.106
Pericalcerine		0.553	0.708
Postcentral		2.934	0.301
Posterior cingulate		1.783	0.441
Precentral		2.025	0.415
Precuneus		0.597	0.702
Rostral anterior cingulate		3.205	0.282
Rostral middle frontal		11.339	0.031
Superior frontal		8.639	0.089
Superior parietal		4.557	0.188
Superior temporal		7.319	0.083
Supramarginal		2.903	0.295
Temporal pole		6.534	0.093
Transverse temporal		14.344	< 0.001

p_BHadj, 5% False Discovery Rate Benjamini–Hochberg adjusted p value; ROI region of interest. Significant results are highlighted in bold.