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. 2020 Nov 13;11:5754. doi: 10.1038/s41467-020-19595-y

Fig. 2. Effect of inbreeding depression on cardiometabolic disease-associated traits in the AWI-Gen cohort.

Fig. 2

To allow comparison between traits, effects estimates (βFROH) and 95% confidence intervals are shown in units of within-group standard deviations. A regular Bonferroni correction for multiple testing was applied; significance is shown with an asterisk (0.05/14). a Normalized (βFROH) and 95% confidence intervals on 14 quantitative traits known to be cardiometabolic disease-associated traits: socio-economic status (SES.Q); six anthropometric traits, height, weight, body mass index (BMI), waist-to-hip ratio (WHR), visceral adipose tissue (VAT) and subcutaneous adipose tissue (SCAT); four classical blood lipids, high and low density lipoprotein cholesterol (HDL, LDL), total cholesterol (TC), and triglycerides (TG); and three circulatory traits, pulse rate, systolic blood pressure (Systolic BP) and diastolic blood pressure (Diastolic BP). Sample sizes, effect estimates in measurement units, standard deviations and p-values are shown in Table S1. b Differences in the effects of normalised (βFROH) and 95% confidence intervals between sites with an average night-light intensity below and above 5. Sample sizes, effect estimates in measurement units, standard deviations and p-values for dwellers living in sites with average night-light intensity below and above 5 are shown in Tables S2 and S3 respectively.