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. 2020 Nov 13;11:5754. doi: 10.1038/s41467-020-19595-y

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — As in the previous figure effects estimates and coefficients were standardized using within-sex standard deviations. Effects estimates (β_FROH) and 95% confidence intervals are shown in units of within-sex standard deviations. The effect of F_ROH in men versus that in women is shown for 9 traits for which there was evidence of significant differences in the effects between sexes. Traits such as body mass index (BMI), subcutaneous adipose tissue (SCAT), low density lipoprotein cholesterol (LDL) and total cholesterol (TC) showed sex-specific effects of opposite direction, positive in women but negative in men. For just two traits, visceral adipose tissue (VAT) and height, the magnitude of effect was greater in women.