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. 2020 Nov 13;187(12):656. doi: 10.1007/s00604-020-04633-9

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Scheme 1 — Schematic presentation of a skin membrane enclosed in a Franz cell. The skin was covered by PW microparticles. The lower chamber was filled with PBS containing H₂O₂ and 14 mM NaN₃. With time, the H₂O₂ permeated the skin membrane and converted PW to PB. The development of blue colour was photographed using a USB microscope. The microscopy images revealed dominant H₂O₂ permeability pathways and the development rate of the blue area could be estimated