Table 1.

Selected MicroRNAs Involved in the Regulation of Glycolysis Processes in Various Cancers

Cancer	MicroRNAs	Expression in Cancer	Target	Model	Samples	References
Pancreatic cancer	miR-124	downregulation	MCT1, PANC-1	in vitro		78
	miR-7	downregulation	LKB1-AMPK-mTOR	in vitro		79
	miR-135	upregulation	phosphofructokinase-1	in vitro, in vivo		80
Glioma	miR-218	upregulation	HK2, Bim1	in vitro, human	21	81
	miR-150	upregulation	HIF-1α	in vitro		82
	miR-451	downregulation	GLUT1	in vitro		83
	miR-200b	downregulation	LDHA	in vitro		84
Hepatocellular carcinoma	miR-491-5p	downregulation	PKM2	in vitro		85
	miR-142-3p	downregulation	LDHA	in vitro		86
	miR-125b	downregulation	HK2	in vitro, in vivo		87
	miR-125a	downregulation	HK2	in vitro, in vivo		88
	miR-199a-5p	downregulation	HIF-1α	in vitro		89
	miR-505	downregulation	IGF-1R	in vitro, human	60	90
Liver cancer	miR-34a	downregulation	LDHA	in vitro, human	22	91
	miR-139-5p	downregulation	HK1, PFKFB3	in vitro, in vivo		92
Gastric cancer	miR-21-5p	upregulation	PDHA1	human	46	93
	miR-34a	downregulation	LDHA	human	73	94
	miR-214	upregulation	A2AR, PRDM16	in vitro		95
	miR-139-5p	downregulation	PRKAA1	in vitro		96
	miR-148b	downregulation	GLUT1	in vitro		97
	miR-181b	downregulation	HK2	in vitro		98
Renal cell carcinoma	miR-409-3p	downregulation	PDK1	in vitro		99
	miR-143	downregulation	K-RAS	in vitro, in vivo, human		100
Osteosarcoma	miR-15b-5p	downregulation		in vitro		101
	miR-323a-3p	downregulation	LDHA	in vitro		102
	miR-33b	downregulation	LDHA	in vitro		103
	miR-125b	downregulation	HK2	in vitro		104
	miR-186	downregulation	PTTG1 and HIF-1	in vitro		105
	miR-150	downregulation	Glut1	in vitro		106
	miR-185	downregulation	hexokinase 2	in vitro, human	30	107
Testicular tumors	miR-199a-3p	downregulation	LDHA, Sp1	in vitro		108
Tongue squamous cell carcinoma	mitomiR-2392	upregulation	HK2 and PKM2	in vitro, in vivo		109
Breast cancer	miR-27b	upregulation	PDHX	in vitro		110
	miR-31	downregulation	DNMT3	in vitro		111
	miR-155	upregulation	PIK3R1-PDK/AKT-FOXO3a-cMYC	in vitro		112
	miR-340	downregulation	MCU	in vitro		113
	miR-30a-5p	downregulation	LDHA	in vitro		114
	miR-342-3p	downregulation	MCT1	in vitro, in vivo, human	146	115
Lung cancer	miR-31-5p	upregulation	HIF-1α inhibitor	in vitro, in vivo		116
	miR-214	upregulation	HK2, PKM2, PTEN/Akt/mTOR	in vitro		117
	miR-449a	downregulation	LDHA	in vitro		118
	miR-124	downregulation	AKT-GLUT1/HK2	in vitro		119
	miR-155	upregulation	HK2	in vitro		120
	miR-144	downregulation	GLUT1	in vitro		121
Ovarian cancer	miR-14	upregulation	HK2, DNMT3A	in vitro		122
	miR-603	downregulation	HK2	human	21	123
	miR-21	upregulation	HK2, PKM2, and LDHA	in vitro		124
	miR-383	downregulation	LDHA	in vitro		125
	miR-203	upregulation	PDHB	in vitro, in vivo		126
	miR-450a	downregulation	TIMMDC1, MT-ND2, ACO2, ATP5B	in vitro, in vivo		127
	miR-603	upregulation	HK2	in vitro, in vivo, human	21	123
Gall bladder carcinoma	miRNA-139-5p	downregulation	PKM2	in vitro, in vivo		128
	let-7a-5p	upregulation	PKM2, Stat3	in vitro		129
	miR-30d-5p	downregulation	LDHA	human		130
Laryngeal squamous cell carcinoma	miR-125b-5p	downregulation	HK2	in vitro, human		131
Prostate cancer	miR-29c	downregulation	SLC2A3	in vitro, human	57	132
	miR-137	upregulation	NOX4	in vitro		133
	miR-101	downregulation	NADPH, TIGAR	in vitro		134
	miR-132	downregulation	GLUT1	in vitro		135
Bladder cancer	miR-200c	downregulation	LDHA	in vitro		136
	miR-361-5p	downregulation	Sp1/PKM2	in vitro		137
	miR-145	downregulation	KLF4/PTBP1/PKMs	in vitro		138
	miR-204-3p	downregulation	LDHA	in vitro, human	60	139
Melanoma	miR-625-5p	downregulation	PKM2	in vitro		140
	miR-137	downregulation	GLO1	in vitro		141
	miR-33a-5p	downregulation	HIF-1α	in vitro, human	20	142
	miR-33b	downregulation	HIF-1α	in vitro		143
	miR-370	upregulation	PDHB	human	41	144
Colorectal cancer	miR-23a∼27a∼24 cluster	upregulation	HIF-1α	in vitro		145
	miR-9-5p, miR-98-5p, and miR-199-5p	upregulation	HK2	human	40	146
	miR-142-5p	upregulation	SDHB	in vitro		147
	miR-328	downregulation	SLC2A1/GLUT1	human	47	148
	miR-1	downregulation	HIF-1α, HK2, MCT4	in vitro, in vivo		149
	miR-98	upregulation	HK2	in vitro, human	215	150
Esophageal squamous cell carcinoma	miR-143	downregulation	HK2	in vitro, human	8	151
Nasopharyngeal carcinoma	miR-34b-3, miR-449a	downregulation	LDHA	in vitro		152
Cutaneous squamous cell carcinoma	miR-365	upregulation	HK2, GLUT1, PDK1	in vitro		153
Oral squamous cell carcinoma	miR-143	downregulation	HK2	in vitro		154
Thyroid cancer	miR-125a-5p	downregulation	CD147	in vitro		155
	miR-143	downregulation	HK2	in vitro, in vivo		156