Table 3. Outcomes of Patients With Nonischemic Fractional Flow Reserve (>0.80) After Propensity Score Weighting.
| Outcome | Follow-up time | No PCI, % [Reference] | PCI, % | Risk difference (95% CI)a | Hazard ratio (95% CI)b |
|---|---|---|---|---|---|
| Primary outcome | |||||
| MACEc | 30 d | 1.5 | 3.1 | 1.6 (0.3 to 3.1) | 2.11 (1.26 to 3.54) |
| 1 y | 6.5 | 10.6 | 4.1 (1.7 to 6.7) | 1.67 (1.27 to 2.21) | |
| 5 y | 24.4 | 33.3 | 8.9 (3.1 to 14.7) | 1.37 (1.14 to 1.65) | |
| Secondary outcomes | |||||
| Death | 30 d | 0.4 | 0.2 | −0.2 (−0.5 to 0.0) | 0.41 (0.12 to 1.42) |
| 1 y | 2.5 | 2.1 | −0.4 (−1.6 to 1.1) | 0.84 (0.44 to 1.61) | |
| 5 y | 13.9 | 15.0 | 1.1 (−3.3 to 5.9) | 0.94 (0.68 to 1.29) | |
| Myocardial infarction | 30 d | 0.6 | 2.0 | 1.4 (0.3 to 2.7) | 3.56 (1.70 to 7.46) |
| 1 y | 1.8 | 3.5 | 1.7 (0.4 to 3.4) | 2.05 (1.26 to 3.32) | |
| 5 y | 5.0 | 8.5 | 3.5 (0.8 to 6.3) | 1.69 (1.20 to 2.37) | |
| Unstable angina | 30 d | 0.5 | 1.4 | 0.9 (0.0 to 2.1) | 3.02 (1.26 to 7.24) |
| 1 y | 2.4 | 5.7 | 3.3 (1.4 to 5.4) | 2.40 (1.63 to 3.52) | |
| 5 y | 7.8 | 13.4 | 5.6 (2.1 to 9.7) | 1.78 (1.35 to 2.35) | |
| Urgent coronary revascularizationd | 30 d | 0.2 | 0.2 | 0 (−0.3 to 0.3) | 0.97 (0.27 to 3.45) |
| 1 y | 1.1 | 2.4 | 1.3 (0.2 to 2.5) | 2.20 (1.29 to 3.74) | |
| 5 y | 3.9 | 7.3 | 3.4 (0.6 to 6.2) | 1.76 (1.21 to 2.57) | |
Abbreviations: MACE, major adverse cardiac events; PCI, percutaneous coronary intervention.
a
Risk differences were estimated from weighted cumulative incidence curves along with 95% CIs generated in 2000 bootstrap resamples.
b
Hazard ratios and 95% CIs were estimated from weighted cause-specific proportional hazards models.
c
MACE was defined by death, myocardial infarction, unstable angina, or urgent coronary revascularization.
d
Urgent coronary revascularization was defined as unplanned hospitalization with percutaneous coronary intervention or coronary artery bypass grafting occurring during the same hospitalization.