Table 1.
Demographic and clinical characteristics of nAMD patients and controls
| All (N = 217) | Control (N = 43) | nAMD (N = 174) | P value | |
|---|---|---|---|---|
| Age, mean (range) | 77.3 (53–93) | 73.4 (58–92) | 78.3 (53–93) | 0.001a |
| Female, number (%) | 110 (51) | 19 (44) | 91 (52) | 0.341b |
| Family history of AMD, number (%) | 46 (21) | 6 (14) | 40 (23) | 0.210b |
| History of hypertension, number (%) | 133 (62) | 23 (53) | 110 (63) | 0.312b |
| History of diabetes, number (%) | 28 (13) | 2 (5) | 26 (15) | 0.078b |
| History of cardiovascular disease, number (%) | 57 (26) | 9 (21) | 48 (28) | 0.416b |
| Smoking status | 0.558b | |||
| Non-smoker, number (%) | 90 (42) | 20 (47) | 70 (40) | |
| Former smoker, number (%) | 109 (51) | 20 (47) | 89 (51) | |
| Current smoker, number (%) | 17 (8) | 2 (5) | 15 (9) | |
| Body Mass Index (Mean ± SD) | 26.0 ± 4.4 | 26.1 ± 5.1 | 26.0 ± 4.2 | 0.967c |
| Taking Cardiovascular Drugs, number (%) | 156 (72) | 28 (65) | 128 (74) | 0.370b |
| Taking Vitamins, number (%) | 49 (23) | 3 (7) | 46 (26) | 0.007b |
| Takin low-dose aspirin, number (%) | 73 (34) | 5 (12) | 68 (39) | 0.001b |
aMann Whitney U test
bPearson’s chi-square test
cIndependent sample t-test