Table 2.
Univariate analysis of prognostic factors
| Characteristics | Median OS | P value | HR | 95% CI for HR |
|---|---|---|---|---|
| Age at diagnosis | < 0.001 | |||
| 40–44 years | 42 | Reference | ||
| 45–49 years | 41 | 1.013 | 0.829–1.237 | |
| 50–54 years | 39 | 1.103 | 0.915–1.329 | |
| 55–59 years | 32 | 1.364 | 1.139–1.634 | |
| Race | < 0.001 | |||
| White | 41 | Reference | ||
| Black | 28 | 1.498 | 1.315–1.707 | |
| Other a | 38 | 1.003 | 0.824–1.220 | |
| Marital status | < 0.001 | |||
| Single | 32 | Reference | ||
| Married | 42 | 0.723 | 0.638–0.819 | |
| Other b | 35 | 0.903 | 0.772–1.057 | |
| Insurance | < 0.001 | |||
| Uninsured | 26 | Reference | ||
| Insured | 38 | 0.633 | 0.513–0.781 | |
| Grade | < 0.001 | |||
| I | 48 | Reference | ||
| II | 44 | 1.214 | 0.953–1.547 | |
| III or IV | 28 | 2.071 | 1.634–2.625 | |
| Histology | 0.003 | |||
| Ductal | 36 | Reference | ||
| Lobular | 44 | 0.748 | 0.624–0.897 | |
| Others | 40 | 0.856 | 0.713–1.028 | |
| Laterality | 0.084 | |||
| Right | 38 | Reference | ||
| Left | 38 | 1.058 | 0.949–1.179 | |
| Bilateral, single primary | 13 | 2.254 | 1.008–5.039 | |
| Tumour subtype | < 0.001 | |||
| HR+/HER2- | 39 | Reference | ||
| HR+/HER2+ | 52 | 0.747 | 0.640–0.873 | |
| HR−/HER2- | 11 | 3.571 | 3.071–4.152 | |
| HR−/HER2+ | 35 | 1.132 | 0.917–1.397 | |
| Bone+Lung metastases | < 0.001 | |||
| No | 42 | Reference | ||
| Yes | 23 | 1.888 | 1.679–2.123 | |
| Bone+Liver metastases | < 0.001 | |||
| No | 44 | Reference | ||
| Yes | 22 | 2.182 | 1.950–2.443 | |
| Bone+Brain metastases | < 0.001 | |||
| No | 40 | Reference | ||
| Yes | 14 | 2.674 | 2.245–3.184 | |
| Only bone metastases | < 0.001 | |||
| No | 46 | Reference | ||
| Yes | 24 | 2.29 | 2.04–2.559 | |
| Surgery | < 0.001 | |||
| No | 32 | Reference | ||
| Yes | 52 | 0.496 | 0.433–0.568 |
Other a (American Indian/AK Native, Asian/Pacific Islander)
Other b (divorced/widowed/separated).