Table 3.
Drug resistance conferring mutations from the current study
| Accession number | Mutations | Drug resisted | HBsAg sero status |
|---|---|---|---|
| MT185643 | Y126H | Adefovir dipivoxil(ADV) | Negative |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| MT185642 | Y126H | Adefovir dipivoxil(ADV) | Negative |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| MT185644 | Y126H | Adefovir dipivoxil(ADV) | Positive |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| MT185645 | Y126H | Adefovir dipivoxil(ADV) | Negative |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| S202G | Entecavir & Lamivudine | ||
| MT185646 | Y126H | Adefovir dipivoxil(ADV) | Negative |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| MT185647 | Y126H | Adefovir dipivoxil(ADV) | Negative |
| M129L | Lamivudine | ||
| V163I | Lamivudine | ||
| MT185648 | M129L | Lamivudine | Negative |
| V163I | Lamivudine | ||
| MT185649 | M129L | Lamivudine | Positive |
| V163I | Lamivudine | ||
| MT185650 | M129L | Lamivudine | Negative |
| V163I, | Lamivudine | ||
| A181T | Lamivudine (zeffix), Adefovir(Hepsera), Telbivudine(Tyzeka and Sebivo) |
These mutations were identified using two online tools Geno2Pheno HBV database (HBVdb) (https://hbv.geno2pheno.org/) and HBVseq program from HIV Stanford database (https://hivdb.stanford.edu/HBV/HBVseq/development/HBVseq.html). The mutations are listed for each of the sample where they occurred