Table 4.

Univariate and Multivariate logistic regression analysis of EOGC and LOGC patients from our hospital for metastasis

Variables	Univariate analysis	P value	Multivariate analysis	P value
Sex
Male	Reference	–
Female	0.846(0.425–1.686)	0.635
Age
≤ 45	Reference	–	Reference	–
> 45	0.395(0.185–0.84)	0.016	0.301(0.135–0.672)	0.003
Hypertension
No	Reference	–
Yes	1.165(0.465–2.918)	0.745
Diabetes
No	Reference	–
Yes	1.506(0.594–3.819)	0.389
Smoke
Never	Reference	–	Reference	–
Yes	2.177(1.142–4.152)	0.018	2.768(1.355–5.657)	0.005
Primary site
Cardia	Reference	–
Fundus	–	–
Antrum	0.807(0.097–6.741)	0.843
Body	1.412(0.164–12.121)	0.753
Overlappping/NOS
T stage
T1	Reference	–	Reference	–
T2	4.102(0.794–21.193)	0.092	3.377(0.584–19.536)	0.174
T3	5.211(1.035–26.233)	0.045	2.141(0.312–14.684)	0.438
T4	4.714(1.094–20.317)	0.038	1.873(1.327–12.112)	0.047
N stage
N0	Reference	–	Reference	–
N1	1.819(0.603–5.493)	0.288	1.028(0.306–3.458)	0.964
N2	2.719(0.651–4.726)	0.266	1.085(0.361–3.262)	0.884
N3	6.564(1.519–8.526)	0.004	2.102(1.064–5.858)	0.035
Lesion classification
Infiltration type	Reference	–
Ulcerative type	0.601(0.194–1.86)	0.377
Protuberant type	0.408(0.093–1.794)	0.235
Lymphatic vessel invasion
No	Reference	–	Reference	–
Yes	4.232(1.91–9.374)	0.000	3.294(1.771–9.268)	0.024
Tumor size
≤ 2 cm	Reference	–
≤ 5 cm	0.259(0.734–6.952)	0.155
> 5 cm	2.965(0.986–8.917)	0.053
Examined LNs
≤ 16	Reference	–
> 16	0.595(0.269–1.317)	0.2