Table 2.
AD-A group (60 cases) | AD-NA group (64 cases) | P value | |
---|---|---|---|
Global cognitive function | |||
MMSEc [points, median (quartile)] | 18.0(10.0 ~ 25.0) | 26.0(21.3 ~ 29.0) | 0.000* |
Memory | |||
AVLTd−Immediate recall [points, median (quartile)] | 9.0(6.0 ~ 12.0) | 13.0(8.8 ~ 17.0) | 0.001* |
AVLT-Short-delayed recall [points, median (quartile)] | 0(0 ~ 3.0) | 2.5(0 ~ 6.5) | 0.000* |
AVLT-long-delayed recall [points, median (quartile)] | 0(0 ~ 3.0) | 3.0(0 ~ 6.0) | 0.003 |
Attention | |||
SDMTe [points, median (quartile)] | 22.0(12.0 ~ 29.0) | 21.0(15.0 ~ 38.0) | 0.445 |
TMTf-A-time consuming [seconds, median (quartile)] | 108.0(67.0 ~ 187.5) | 75.0(60.0 ~ 122.0) | 0.075 |
Executive function | |||
SCWTg [points, median (quartile)] | 46.5(41.5 ~ 49.25) | 48.0(42.3 ~ 50.0) | 0.265 |
TMT-B- time consuming [seconds, median (quartile)] | 238.0(194.0 ~ 240.0) | 222.0(168.5 ~ 240.0) | 0.550 |
Language | |||
AFTh (points, mean ± SD) | 11.5(8.3 ~ 14.8) | 15.5(12.0 ~ 20.0) | 0.000* |
Visuospatial function | |||
CFTi-Copy [points, median (quartile)] | 22.0(5.0 ~ 32.0) | 26.0(10.5 ~ 34.0) | 0.427 |
Neuropsychiatric symptoms | |||
HAMDj [points, median (quartile)] | 10.0(3.0 ~ 15.0) | 4.0(1.0 ~ 8.0) | 0.001* |
HAMAk [points, median (quartile)] | 6.0(3.0 ~ 12.0) | 3.0(0 ~ 6.0) | 0.004 |
CMAIl [points, median (quartile)] | 29.0(29.0 ~ 38.0) | 29.0(29.0 ~ 29.0) | 0.000* |
Activities of daily living | |||
BADLm [points, median (quartile)] | 6.0(6.0 ~ 10.0) | 6.0(6.0 ~ 6.0) | 0.001* |
IADLo [points, median (quartile)] | 11.5(8.0 ~ 25.5) | 8.0(8.0 ~ 11.0) | 0.000* |
*P < 0.002 after Bonferroni correction, aAD-A Alzheimer disease with apathy, bAD-NA Alzheimer disease with no apathy, c Mini-Mental State Examination, dAVLT Auditory Verbal Learning Test, eSDMT Symbol Digit Modalities Test, fTMT Trial Making Test, gSCWT Stroop Color Word Test, hAFT Animal Fluency Test, iCFT Complex Figure Test, jHAMD Hamilton Depression Scale, kHAMA Hamilton Anxiety Scale, lCMAI Cohen- Mansfield Agitation Inventory, mBasic Activity of Daily Living, oInstrucmental Activity of Daily Living