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. 2020 Nov 14;20:416. doi: 10.1186/s12883-020-01978-9

Table 2.

Clinical Symptoms of AD-Aa and AD-NAb groups

AD-A group (60 cases) AD-NA group (64 cases) P value
Global cognitive function
 MMSEc [points, median (quartile)] 18.0(10.0 ~ 25.0) 26.0(21.3 ~ 29.0) 0.000*
Memory
 AVLTd−Immediate recall [points, median (quartile)] 9.0(6.0 ~ 12.0) 13.0(8.8 ~ 17.0) 0.001*
 AVLT-Short-delayed recall [points, median (quartile)] 0(0 ~ 3.0) 2.5(0 ~ 6.5) 0.000*
 AVLT-long-delayed recall [points, median (quartile)] 0(0 ~ 3.0) 3.0(0 ~ 6.0) 0.003
Attention
 SDMTe [points, median (quartile)] 22.0(12.0 ~ 29.0) 21.0(15.0 ~ 38.0) 0.445
 TMTf-A-time consuming [seconds, median (quartile)] 108.0(67.0 ~ 187.5) 75.0(60.0 ~ 122.0) 0.075
Executive function
 SCWTg [points, median (quartile)] 46.5(41.5 ~ 49.25) 48.0(42.3 ~ 50.0) 0.265
 TMT-B- time consuming [seconds, median (quartile)] 238.0(194.0 ~ 240.0) 222.0(168.5 ~ 240.0) 0.550
Language
 AFTh (points, mean ± SD) 11.5(8.3 ~ 14.8) 15.5(12.0 ~ 20.0) 0.000*
Visuospatial function
 CFTi-Copy [points, median (quartile)] 22.0(5.0 ~ 32.0) 26.0(10.5 ~ 34.0) 0.427
Neuropsychiatric symptoms
 HAMDj [points, median (quartile)] 10.0(3.0 ~ 15.0) 4.0(1.0 ~ 8.0) 0.001*
 HAMAk [points, median (quartile)] 6.0(3.0 ~ 12.0) 3.0(0 ~ 6.0) 0.004
 CMAIl [points, median (quartile)] 29.0(29.0 ~ 38.0) 29.0(29.0 ~ 29.0) 0.000*
Activities of daily living
 BADLm [points, median (quartile)] 6.0(6.0 ~ 10.0) 6.0(6.0 ~ 6.0) 0.001*
 IADLo [points, median (quartile)] 11.5(8.0 ~ 25.5) 8.0(8.0 ~ 11.0) 0.000*

*P < 0.002 after Bonferroni correction, aAD-A Alzheimer disease with apathy, bAD-NA Alzheimer disease with no apathy, c Mini-Mental State Examination, dAVLT Auditory Verbal Learning Test, eSDMT Symbol Digit Modalities Test, fTMT Trial Making Test, gSCWT Stroop Color Word Test, hAFT Animal Fluency Test, iCFT Complex Figure Test, jHAMD Hamilton Depression Scale, kHAMA Hamilton Anxiety Scale, lCMAI Cohen- Mansfield Agitation Inventory, mBasic Activity of Daily Living, oInstrucmental Activity of Daily Living