Fig. 3.

a ChIP-seq read densities of C11orf95-RELA¹⁴²⁵ and H3K27ac in BXD-1425-EPN cells. 3792 top-scoring C11orf94-RELA¹⁴²⁵ ChIP-seq peaks were used to plot the heatmap. The left side heatmap showed C11orf95-RELA¹⁴²⁵ signals along a 5 kb region centering the peak summit. The right side heatmap showed H3K27ac signals along the same regions. b Read densities of H3K27ac and C11orf95-RELA^fus1 in G16-4 cells. 441 differential H3K27ac peaks in G16-4 compared to G16-2 cells were used to plot the heatmap. The left side heatmap showed H3K27ac signals along a 5 kb region centered with H3K27ac peak center. The right side heatmap showed C11orf95-RELA^fus1 signals along the same regions. c RELA, C11orf95^fus1, C11orf95-RELA^fus1 and C11orf95-RELA¹⁴²⁵ as well as corresponding H3K27ac ChIP-seq profiles at ST-EPN-RELA marker genes CCND1 and L1CAM