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. 2020 Oct 23;11(6):398–404. doi: 10.14740/cr1159

Table 3. Cardiac Troponin-I Level as a Predictor of Mortality in Patients with COVID-19.

Statistic Value 95% confidence interval
Sensitivity 66% 52.1% - 78.1%
Specificity 83% 77.0% - 87.9%
Positive likelihood ratio 3.89 2.71 - 5.57
Negative likelihood ratio 0.41 0.28 - 0.59
Disease (mortality) prevalence 21.7% (mortality)*
Positive predictive value 51.9% 43% - 60.7%
Negative predictive value 89.7% 85.8% - 92.7%
Accuracy 79.3% 73.8% - 84.1%

*The prevalence of all-cause in-hospital mortality for the study population. Sensitivity, specificity, disease (mortality) prevalence, positive and negative predictive value as well as accuracy are expressed as percentages. Confidence intervals for sensitivity, specificity and accuracy are “exact” Clopper-Pearson confidence intervals. Confidence intervals for the likelihood ratios are calculated using the “Log method” as given on page 109 of Altman et al 2000 [7]. Confidence intervals for the predictive values are the standard logit confidence intervals given by Mercaldo et al 2007 [8]. COVID-19: coronavirus disease 2019.