Table 1. Lp(a) Values in FH and Non-FH Individuals.
| Studies | Genea | FH (-) |
FH (+) |
||||||
|---|---|---|---|---|---|---|---|---|---|
| Subjects (n) | Age (years) | Lp(a) (mg/dL)b | LDL-C (mmol/L)c | Subjects (n) | Age (years) | Lp(a) (mg/dL)b | LDL-C (mmol/L)c | ||
| Lingenhel et al, 1998 [5] | LDLR | 57 | - | 16.3 | 5.3 | 103 | - | 27.7 | 8.7 |
| Alonso et al, 2014 [6] | LDLR | 957 | 40.6 | 21 | 3.4 | 1,960 | 44.4 | 23.6 | 4.8 |
| Tada et al, 2016 [7] | LDLR | 4,015 | 58 | 11.8 | 2.8 | 198 | 42 | 21.9 | 5.6 |
| PCSK9 | - | - | - | - | 42 | 52 | 21.1 | 6.1 | |
aGene used for diagnosis of FH; bLp(a) expressed as a median value; cLDL-C expressed as a mean value. FH: familial hypercholesterolemia; Lp(a): lipoprotein(a); LDL-C: low-density lipoprotein cholesterol; LDLR: low-density lipoprotein receptor; PCSK9: proprotein convertase subtilisin/kexin type 9.