Table 1.
Patient- and Transplant-related Characteristics and Post-transplant Outcomes.
| Study | Study type and study period | n (Male sex) | Median (range) age, years | Regimen intensity | Median F/U, months | CR | OS | Relapse | NRM |
|---|---|---|---|---|---|---|---|---|---|
| Tsimberidou et al. 2006 [14] | Single institution (1975–2005) | 17 (Male = 11) | 60 (35–72) | MAC = 2 RIC = 15 |
NE | 6% | 75% In CR/CRu/PR (3-y) | 21% | 12% |
| Cwynarski et al. 2012 [31] | EBMT registry (1997–2007) | 25 (Male = 15) | 57 (31–70) | MAC = 7 RIC = 18 |
29% | NE | 36% (3-y) | 47% (3-y) | 26% (3-y) |
| In CR/Cru/PR 41% (3-y) |
MAC = 43% RIC = 19% (3-y) |
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| In refractory disease 17% (3-y) |
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| Rozovski et al. 2015 [30] | Single institution (1998–2011) | 20 (NE) | 58 (32–72) | MAC = 6 RIC = 14 |
45 | 35% | 36% (2-y) 0 (5-y) |
NE | NE |
| Kharfan-Dabaja et al. 2017 [29] | Single institution (2008–2016) | 10 (Male = 5) | 63 (50–74) | MAC = 7 RIC = 3 |
46 | 70% | 50% (4-y) | 10% (4-y) | 40% (4-y) |
Note. F/U= follow up; CR = complete remission; Cru = complete remission undetermined; EBMT = European Society for Blood and Marrow Transplantation; MAC = myeloablative conditioning; mo = month; n = number of patients; NE = no extractable/not available data; NRM = non-relapse mortality; OS = overall survival; PR = partial response; RIC = reduced intensity conditioning; y = year.