Table 2.
Baseline characteristics and treatment outcome of patients with completely resected diffuse large B‐cell lymphoma in comparison to incompletely resected stage I patients from the PETAL cohort
| Completely resected lymphoma | Incompletely resected lymphoma | P | |
|---|---|---|---|
| No. of stage I patients | 48 | 115 | |
| Baseline characteristics | |||
| Age ≥ 60 years | 20 (41.7%) | 63 (54.8%) | .169 |
| Male sex | 33 (68.8%) | 77 (67.0%) | .857 |
| ECOG performance status ≥ 2 | 0 (0.0%) | 3 (2.8%) | .557 |
| Lactate dehydrogenase > ULN | 5 (10.4%) | 32 (27.8%) | .015 |
| Superficial lymphoma location | 36 (75.0%) | 49 (42.6%) | <.001 |
| Treatment outcome | |||
| Complete remission rate | 44/44 (100.0%) | 89/108 (82.4%) | .02 |
| Overall response rate | 44/44 (100.0%) | 106/108 (98.1%) | 1.0 |
| 2‐year progression‐free survival (95% CI) | |||
| All ages | 92.7% (84.7‐100) | 88.4% (82.5‐94.3) | .056 |
| <60 years a | 100% (n.a.) | 92.2% (84.8‐99.6) | .031 |
| ≥60 years a | 83.6% (66.5‐100) | 85.3% (76.5‐94.1) | .453 |
| 2‐year overall survival (95% CI) | |||
| All ages | 92.7% (84.7‐100) | 93.7% (89.2‐98.2) | .176 |
| <60 years a | 100% (n.a.) | 95.9% (90.2‐100) | .075 |
| ≥60 years a | 83.6% (66.5‐100) | 90.1% (82.5‐97.7) | .541 |
Abbreviations: CI, confidence interval; ECOG, Eastern Cooperative Oncology Group; PETAL, Positron Emission Tomography‐guided Therapy of Aggressive non‐Hodgkin Lymphomas; ULN, upper limit of normal.
Response rates are given as number of patients responding/total number of patients with available data.
a
For patient numbers, refer to No. at risk in Figure 2.